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Fórmula lineal:
NH2OH · HCl
Número CAS:
Peso molecular:
69.49
UNSPSC Code:
12352301
NACRES:
NA.22
PubChem Substance ID:
EC Number:
226-798-2
Beilstein/REAXYS Number:
3539763
MDL number:
Assay:
99.995% trace metals basis
Servicio técnico
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Permítanos ayudarleQuality Level
assay
99.995% trace metals basis
form
powder, crystals or chunks
pH
2.5-3.5 (20 °C, 50 g/L)
mp
155-157 °C (dec.) (lit.)
density
1.67 g/mL at 25 °C (lit.)
SMILES string
Cl.NO
InChI
1S/ClH.H3NO/c;1-2/h1H;2H,1H2
InChI key
WTDHULULXKLSOZ-UHFFFAOYSA-N
Application
Reactant for preparation of:
- Organosilane amines as potent inhibitors and structural probes of influenza A virus M2 proton channel
- Lamellarin D analogues as inibitors of topoisomerase I and potential antitumor agents
- Azapeptide tocolytic agents as inhibitors of prostaglandin F2α receptor for preventing preterm labor
- Thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B
- Orally bioavailable quinoline-based antidiabetic dipeptidyl peptidase IV inhibitors targeting Lys554
- Pyrimidine nucleoside derivatives with nitric oxide donors as antiviral agents
- Benzyladenosine compounds targeting adenosine A2A receptor and adenosine transporter for neuroprotection
- Naphthol derivatives as inhibitors of the vanilloid receptor TRPV1 with improved potency in rat cystometry models of urinary incontinence
Biochem/physiol Actions
MAO inhibitor; inhibits platelet aggregation.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral
target_organs
spleen
Clase de almacenamiento
4.1A - Other explosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Dipeptidyl peptidase IV (DPP-4) inhibition is a validated therapeutic option for type 2 diabetes, exhibiting multiple antidiabetic effects with little or no risk of hypoglycemia. In our studies involving non-covalent DPP-4 inhibitors, a novel series of quinoline-based inhibitors were designed
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