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Merck

479306

cis-Diamineplatinum(II) dichloride

≥99.9% trace metals basis

Sinónimos:

cis-Diammineplatinum(II) dichloride, cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cisplatin

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About This Item

Fórmula lineal:
Pt(NH3)2Cl2
Número CAS:
15663-27-1
Peso molecular:
300.05
NACRES:
NA.22
PubChem Substance ID:
24871609
UNSPSC Code:
12161600
EC Number:
239-733-8
MDL number:
MFCD00011623

Nombre del producto

cis-Diamineplatinum(II) dichloride, ≥99.9% trace metals basis

InChI key

LXZZYRPGZAFOLE-UHFFFAOYSA-L

InChI

1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

SMILES string

N.N.Cl[Pt]Cl

assay

≥99.9% trace metals basis

reaction suitability

core: platinum
reagent type: catalyst

mp

270 °C (lit.)

antibiotic activity spectrum

neoplastics

mode of action

DNA synthesis | interferes

Quality Level

100

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Application

cis-Diamineplatinum(II) dichloride can be used as a model drug to test the efficiency of various drug carriers in drug delivery.
Highly active chemotherapeutic agent for use in preventing the advancement of testicular cancer.

Biochem/physiol Actions

Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
MKCZ9966
MKCZ2360
MKCX3349
MKCV6980
MKCX0285

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How can I get Product 479306, cis-Diammineplatinum(II) dichloride, in solution?

    cis-Diammineplatinum(II) dichloride is soluble in water at 25°C. It is also soluble in N,N-dimethylformamide (DMF), dimethylacetamide and dimethyl sulfoxide (DMSO). We do not test solution stability of this product. However, we do have stability data on a document on another cis-Diammineplatinum(II) dichloride product; the product number is P4394.

  4. How should Product 479306, cis-Diammineplatinum(II) dichloride be stored?

    This product should be stored at room temperature.

  5. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  6. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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