P45850
Pipecolinic acid
98%, for peptide synthesis
Sinónimos:
(±)-Piperidine-2-carboxylic acid, 2-Piperidinecarboxylic acid, Homoproline, Pipecolic acid free base
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Fórmula empírica (notación de Hill):
C6H11NO2
Número CAS:
Peso molecular:
129.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
208-616-3
MDL number:
Beilstein/REAXYS Number:
81095
Servicio técnico
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Permítanos ayudarleNombre del producto
Pipecolinic acid, 98%
Quality Level
assay
98%
form
powder and chunks
reaction suitability
reaction type: solution phase peptide synthesis
technique(s)
LC/MS: suitable
color
white to beige
mp
282 °C (dec.) (lit.)
SMILES string
OC(=O)C1CCCCN1
InChI
1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)
InChI key
HXEACLLIILLPRG-UHFFFAOYSA-N
General description
Pipecolinic acid also known as 2-piperidinecarboxylic acid, is a versatile reagent used in the solution phase peptide synthesis. It has been commonly utilized as a replacement for proline in many peptidomimetic syntheses.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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D M Danks et al.
The Journal of pediatrics, 86(3), 382-387 (1975-03-01)
Studies of eight patients with this syndrome confirm the characteristic pattern of abnormalities and the autosomal recessive mode of inheritance. The incidence is estimated to be approximately 1 in 100,000 live births. The liver lesion proved to be variable, with
Conformational heterogeneity about pipecolic acid peptide bonds: conformational, thermodynamic, and kinetic aspects
WJ Wu
The Journal of Organic Chemistry, 63, 6689-6698 (1998)
B T Poll-The et al.
Journal of inherited metabolic disease, 9(2), 169-174 (1986-01-01)
Infantile Refsum's disease was diagnosed in three male patients, presenting with facial dysmorphia, retinitis pigmentosa, neurosensory hearing loss, hepatomegaly, osteopenia and delayed growth and psychomotor development. An elevated plasma phytanic acid concentration and a deficient phytanic acid oxidase activity in