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Merck

1.03669

Glicina

granulated, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

Sinónimos:

Glicocola, Ácido aminoacético, Ácido aminoetanoico

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Fórmula lineal:
NH2CH2COOH
Número CAS:
Peso molecular:
75.07
EC Index Number:
200-272-2
UNSPSC Code:
12352209
Beilstein/REAXYS Number:
635782
MDL number:
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Quality Segment

agency

BP, ChP, JP, Ph. Eur., USP

vapor pressure

0.0000171 Pa ( 25 °C)

description

granulated EMPROVE® EXPERT Ph.Eur.,BP,JP,USP

product line

EMPROVE® EXPERT

assay

99.0-101.0% (calculated on dried substance, perchloric acid titration)

form

granular

technique(s)

inhibition assay: suitable

pH

5.9-6.4 (20 °C, 50 g/L in H2O)

pKa (25 °C)

(1) 2.35, (2) 9.60, 2.35

mp

240 °C (dec.) (lit.)

density

1.161 g/cm3 at 20 °C

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical

storage temp.

2-30°C

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

General description

Standard bulk materials often show a tendency for caking, clumping and dust formation which results in laborious weighing processes and manual de-caking processes with a negative impact on manufacturing efficiency. Due to its granulated form, granulated glycine is free-flowing and easy to handle. Its greatly reduced caking behavior facilitates processability, speeds up manufacturing processes and increases operator safety.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Glycine in general is widely used in the biopharma industry as a stabilizer, tonicity modifier, buffer and precipitating agent. It is also used as an emollient, emulsifying agent and solubilizer in solid and semi-solid formulations.
Due to its low microbial and endotoxin limits, Glycine granulated Emprove® Expert is especially suitable for high-risk applications.

Biochem/physiol Actions

Neurotransmisor inhibidor de la médula espinal, regulador alostérico de los receptores NMDA.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

No data available

flash_point_c

No data available



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