AB1570W
Anti-GABA Transporter-1 Antibody
Chemicon®, from rabbit
Sinónimos:
GAT-1
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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
19
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Permítanos ayudarlebiological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rabbit, mouse, monkey, human, rat, feline
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLC6A1(6529)
Categorías relacionadas
General description
67 kDa
Immunogen
Rat GAT-1, C-terminus (aa 588-599)
Application
Anti-GABA Transporter-1 Antibody detects level of GABA Transporter-1 & has been published & validated for use in IH & WB.
Western blotting: 1:200-1:500 (67 kDa)
Immunohistochemistry
Optimal working dilutions must be determined by the end user.
Immunohistochemistry
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes GABA Transporter-1 (GAT-1), C-terminus. No cross-reactivity to the C-termini of other transmitter transporters detected.
Physical form
Affinity Purified antibody. Lyophilized from 0.1 M PBS with 1% BSA and 0.1% sodium azide. Reconstitute with 100 μL of sterile distilled water.
Preparation Note
Maintain lyophilized material at 2–8°C for up to 12 months. Maintain reconstituted materialat -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Brain-derived neurotrophic factor (BDNF) enhances GABA transport by modulating the trafficking of GABA transporter-1 (GAT-1) from the plasma membrane of rat cortical astrocytes.
Vaz, SH; J?rgensen, TN; Cristov?o-Ferreira, S; Duflot, S; Ribeiro, JA; Gether, U; Sebasti?o, AM
The Journal of Biological Chemistry null
Roberta Celli et al.
Neuropharmacology, 178, 108240-108240 (2020-08-10)
Previous studies have shown that injection of the mGlu5 receptor positive allosteric modulator (PAM) VU0360172 into either the thalamus or somatosensory cortex markedly reduces the frequency of spike-and-wave discharges (SWDs) in the WAG/Rij model of absence epilepsy. Here we have
Roberta Celli et al.
Current neuropharmacology, 21(1), 105-118 (2022-05-18)
Previous studies suggest that different metabotropic glutamate (mGlu) receptor subtypes are potential drug targets for treating absence epilepsy. However, no information is available on mGlu3 receptors. To examine whether (i) changes of mGlu3 receptor expression/signaling are found in the somatosensory
Elena E Bagley et al.
Neuron, 45(3), 433-445 (2005-02-08)
Adaptations in neurons of the midbrain periaqueductal gray (PAG) induced by chronic morphine treatment mediate expression of many signs of opioid withdrawal. The abnormally elevated action potential rate of opioid-sensitive PAG neurons is a likely cellular mechanism for withdrawal expression.
Jaime M Hatcher et al.
Experimental neurology, 204(2), 619-630 (2007-02-13)
Numerous epidemiological studies have shown an association between pesticide exposure and an increased risk of developing Parkinson's disease (PD). Here, we provide evidence that the insecticide dieldrin causes specific oxidative damage in the nigrostriatal dopamine (DA) system. We report that
Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| AB1570W | 04053252274961 |
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