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Merck

ABE607

Anti-APOBEC3G Antibody

from rabbit, purified by affinity chromatography

Sinónimos:

DNA dC->dU-editing enzyme APOBEC-3G, APOBEC-related cytidine deaminase, APOBEC-related protein, ARCD, APOBEC-related protein 9, ARP-9, CEM-15, CEM15, Deoxycytidine deaminase

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
1
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

immunohistochemistry: suitable, western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... APOBEC3G(60489)

General description

DNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G) is a member of the cytidine and deoxycytidylate deaminase family. APOBEC3G is a multi-isoform member of the cytidine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates. Similar to TRIM5 alpha which targets incoming retroviral capsids, APOBEC3G plays an important role in cellular defense against retroviral infection. It is expressed in spleen, testes, ovary, peripheral blood leukocytes, and several tumor cell lines.
~46 kDa observed

Immunogen

KLH-conjugated linear peptide corresponding to the N-terminus of human APOBEC3G.

Application

Detect APOBEC-3G using this rabbit polyclonal antibody, Anti-APOBEC3G Antibody validated for use in western blotting & IHC.
Immunohistochemistry Analysis: 1 µg/mL from a representative lot detected APOBEC3G in human spleen tissue.

Biochem/physiol Actions

This antibody recognizes the N-terminus of APOBEC3G.

Analysis Note

Evaluated by Western Blotting/Peptide Inhibition Assay Analysis in Caco-2 cell lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 5 µg/mL of this antibody detected APOBEC3G in 15 µg of Caco-2 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


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Clase de almacenamiento

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Venkata Subba Rao Atluri et al.
Scientific reports, 6, 27864-27864 (2016-06-21)
We have observed significantly increased HIV infection in HIV infected macrophages in the presence of cocaine that could be due to the downregulation of BST2 restriction factor in these cells. In human inflammasome PCR array, among different involved in inflammasome



Número de artículo de comercio global

SKUGTIN
ABE60704053252878817