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F8798

Folic acid

Name: Folic acid
Brand: SIAL

97.0-102.0% dry basis, solid, meets USP testing specifications

Sinónimos:

PteGlu, Pteroyl-L-glutamic acid, Vitamin M

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Fórmula empírica (notación de Hill):

C₁₉H₁₉N₇O₆

Número CAS:

59-30-3

Peso molecular:

441.40

PubChem Substance ID:

24894977

eCl@ss:

34058014

UNSPSC Code:

12352100

NACRES:

NA.21

EC Number:

200-419-0

MDL number:

MFCD00079305

Beilstein/REAXYS Number:

100781

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Propiedades

Nombre del producto

Folic acid, meets USP testing specifications

biological source

synthetic (organic)

Quality Level

300

agency

USP/NF, meets USP testing specifications

assay

97.0-102.0% dry basis

form

solid

color

yellow

mp

>285 °C

application(s)

cell analysis
pharmaceutical (small molecule)

functional group

amide, amine, carboxylic acid

SMILES string

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

InChI

1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

InChI key

OVBPIULPVIDEAO-LBPRGKRZSA-N

Descripción

General description

Folic acid, also known as pteroyl-L-glutamic acid, belongs to the vitamin B group. The conformational analysis of folic acid in the solution has been reported based on nuclear magnetic resonance (NMR) and theoretical calculations. The reaction kinetics of the photodecomposition under ultraviolet radiation has been investigated. This product is a high quality pharmacopoeia product that meets the testing specifications of USP (United States Pharmacopoeia). It can be employed in research and pilot studies.

Application

Folic acid has been used in a study to investigate its protective effects against the toxicity caused by valproic acid (VPA) on maternal liver tissue. It has also been used as standard for the quantification of plasma folic acid by reversed-phase HPLC.

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Clase de almacenamiento

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Ultraviolet photodegradation of folic acid.

Off MK, et al.

Journal of Photochemistry and Photobiology. B, Biology, 80(1), 47-55 (2005)

Ultrastructural investigation of the protective role of folic acid and vitamin E against toxic effects of valproic acid on maternal liver tissue during period of gestation.

Ozlem P Baran et al.

Saudi medical journal, 27(3), 407-409 (2006-03-15)

Solution structure of folic acid: Molecular mechanics and NMR investigation.

Bonechi C, et al.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 60(7), 1411-1419 (2004)

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