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Merck

O5879

Ornidazole

analytical standard

Sinónimos:

1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole

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About This Item

Fórmula lineal:
C7H10N3O3Cl
Número CAS:
Peso molecular:
219.63
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
240-826-0
MDL number:

Nombre del producto

Ornidazole, analytical standard

InChI key

IPWKIXLWTCNBKN-UHFFFAOYSA-N

InChI

1S/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3

SMILES string

Cc1ncc(n1CC(O)CCl)[N+]([O-])=O

grade

analytical standard

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Ornidazole has been used as a standard in the determination of traces of ornidazole in samples of aquaculture tissue using ultra high performance liquid chromatography coupled with mass spectrometry (UHPLC).

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3


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Marta Dolores Mudry et al.
Mutation research, 721(1), 108-113 (2011-01-25)
The genotoxicity of two nitroimidazole derivatives, ornidazole (ONZ) and metronidazole (MTZ) in the peripheral blood lymphocytes of Cebus libidinosus (CLI) (Primates, Cebidae) was assessed. Endpoints measured included sister chromatid exchange (SCE) frequency, cell proliferation kinetics (CPK), replication index (RI), mitotic
Subhash S Vaghani et al.
Carbohydrate research, 347(1), 76-82 (2011-11-22)
In the present study, carboxymethyl chitosan was prepared from chitosan, crosslinked with glutaraldehyde and evaluated in vitro as a potential carrier for colon targeted drug delivery of ornidazole. Ornidazole was incorporated at the time of crosslinking of carboxymethyl chitosan. The
Kriti Shivhare et al.
International journal of biological macromolecules, 106, 775-783 (2017-08-19)
Molecular self-assembly of biodegradable amphiphilic polymers allows rational design of biocompatible nanomaterials for drug delivery. Use of substituted polysaccharides for such applications offers the ease of design and synthesis, and provides higher biofunctionality and biocompatibility to nanomaterials. The present work
Nathalie Mahé et al.
Journal of pharmaceutical sciences, 100(6), 2258-2266 (2011-01-20)
The solid-state properties of antiprotozoal ternidazole (3-(2-methyl-5-nitroimidazol-1-yl)-propan-1-ol) have been studied. Crystals are triclinic in the temperature interval between 100 and 333 K (melting point) with two different molecular conformations present in the asymmetric unit (Z' = 2) and two of
Haozhe Tang et al.
BMC oral health, 17(1), 163-163 (2017-12-30)
We investigated the clinical and radiographic outcomes of autotransplanted teeth over a follow-up period of 2 to 8 years, and summarize the findings of other relevant studies with regard to the primary factors that influence a good prognosis in such patients.

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