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S3674

Ácido succínico

Name: Ácido succínico
Brand: SIAL

BioXtra, BioRenewable, ≥99.0%

Sinónimos:

Ácido butanodióico

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Fórmula lineal:

HOOCCH₂CH₂COOH

Número CAS:

110-15-6

Peso molecular:

118.09

UNSPSC Code:

12352106

NACRES:

NA.25

PubChem Substance ID:

24899568

EC Number:

203-740-4

Beilstein/REAXYS Number:

1754069

MDL number:

MFCD00002789

Assay:

≥99.0%

Servicio técnico

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Propiedades

Quality Level

200

product line

BioXtra

assay

≥99.0%

greener alternative product characteristics

Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

≤0.01% Insoluble matter

ign. residue

≤0.02%

bp

235 °C (lit.)

mp

184-186 °C (lit.)

solubility

H₂O: 0.5 M, clear, colorless

anion traces

chloride (Cl^-): ≤0.001%, sulfate (SO₄^2-): ≤0.003%

cation traces

Al: ≤0.0005%, Ca: ≤0.001%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

greener alternative category

, Aligned

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

Descripción

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is biobased and thus aligns with "Use of Renewable Feedstocks". Click here for more information.

Application

Succinic acid has been used:

in succinate dehydrogenase mitochondrial assay.
as an internal standard in mass spectroscopy.
as succinate dehydrogenase substrate in oxygraph analysis to measure respiration rates.

Biochem/physiol Actions

Succinic acid is a byproduct of anaerobic fermentation in microbes. It is a dicarboxylic acid and an intermediate in Kreb′s cycle. Polymorphism in succinate dehydrogenase leads to succinate accumulation. High levels of succinate impairs 2-oxoglutarate epigenetic signalling. Succinate levels may modulate tumor progression. Succinate inhibits histone demethylation and may contribute to epigenetic changes. Succinate is crucial for interleukin-1 β (IL-1β) synthesis during inflammation and immune signalling.

Other Notes

Succinic Acid: A New Platform Chemical for Biobased Polymers from Renewable Resources

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pictograms

GHS05

signalword

Danger

hcodes

H318

pcodes

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Cardiomyocyte differentiation: Experience and observations from 2 laboratories

Patten VA, et al.

SA heart journal, 14(2), 96-107 (2017)

Succinate: a new epigenetic hacker

Yang M and Pollard PJ

Cancer Cell, 23(6), 709-711 (2013)

Screening For Isolation of Succinic Acid Producing Microbes

Hema N and Sreenath KP

Biosciences, Biotechnology Research Asia, 15(2), 327-333 (2018)

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