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A4403

Ácido L-ascórbico

Name: <SC>Ácido L</SC>-ascórbico
Brand: SIGMA

powder, suitable for cell culture, γ-irradiated

Sinónimos:

Ácido L-treoascórbico, Factor antiescorbútico, Vitamina C

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Fórmula empírica (notación de Hill):

C₆H₈O₆

Número CAS:

50-81-7

Peso molecular:

176.12

UNSPSC Code:

12352207

NACRES:

NA.75

PubChem Substance ID:

24890857

EC Number:

200-066-2

Beilstein/REAXYS Number:

84272

MDL number:

MFCD00064328

Form:

powder

Servicio técnico

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Propiedades

biological source

synthetic (organic)

Quality Segment

200

sterility

γ-irradiated

form

powder

mol wt

M_w 176.12 g/mol

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

color

white to off-white

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

H₂O: 10 mg/mL

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

Descripción

General description

L-ascorbic acid is an unsaturated γ-lactone ring containing an enediol configuration (–COH=COH) attached with a carbonyl group.

Application

For use in cell culture applications as an antioxidant and to regenerate tocopherol.
L-ascorbic acid has been used:

in an osteogenic supplement for the growth of cells
as a component in the differentiation media
in WS-MSCs (Werner syndrome-mesenchymal stem cells) to study rescuing properties of ascorbic acid on aging defects

Biochem/physiol Actions

L-ascorbic acid mainly exhibits antioxidant properties. It protects plants from oxidative stress and mammals from diseases associated with oxidative stress. L-ascorbic acid mainly protects from hydroxyl radicals, superoxide and singlet oxygen. In addition, it also reduces the membrane-linked antioxidant α-tocopherol (oxidised form). L-Ascorbic acid enhances endothelium-dependent vasodilation in various disorders, including diabetes, coronary artery disease, hypertension and chronic heart failure.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c