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C1017

Citrinin

Name: Citrinin
Brand: SIGMA

from Penicillium citrinum, ≥98% (HPLC), powder, mycotoxin

Sinónimos:

(3R,4S)-8-Hydroxy-3,4,5-Trimethyl-6-Oxo-4,6-Dihydro-3H-Isochromene-7-Carboxylic Acid, 4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid

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Fórmula empírica (notación de Hill):

C₁₃H₁₄O₅

Número CAS:

518-75-2

Peso molecular:

250.25

NACRES:

NA.77

PubChem Substance ID:

24892302

UNSPSC Code:

12352200

EC Number:

208-257-2

MDL number:

MFCD00006912

Beilstein/REAXYS Number:

5282243

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

200

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Propiedades

Nombre del producto

Citrinin, from Penicillium citrinum, ≥98% (HPLC)

biological source

Penicillium citrinum

Quality Level

200

assay

≥98% (HPLC)

form

powder

storage temp.

2-8°C

SMILES string

C[C@H]1OC=C2C(O)=C(C(O)=O)C(=O)C(C)=C2[C@@H]1C

InChI

1S/C13H14O5/c1-5-7(3)18-4-8-9(5)6(2)11(14)10(12(8)15)13(16)17/h4-5,7,15H,1-3H3,(H,16,17)/t5-,7-/m1/s1

InChI key

CQIUKKVOEOPUDV-IYSWYEEDSA-N

Descripción

General description

Citrinin is a mycotoxin from Penicillium citrinin that comprises a quinone methide component.

Application

Citrinin has been used as:

a standard for calibration curve preparation for citrinin quantification Monascus purpureus ATCC 36928
an internal standard in thin layer chromatography (TLC) for characterizing the citrinin from Aspergillus and Penicillium strains
standard to characterize citrinin for rotten apples TLC

Biochem/physiol Actions

Citrinin is a predominant contaminant in agriculture supplies and food. It exhibits genotoxic, embryotoxic, and teratogenic properties. It is hepatonephrotoxin and a potent mycotoxin in rice grains.

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H301 + H311 + H331,H351

pcodes

P202 - P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Citrinin in Foods and Supplements: A Review of Occurrence and Analytical Methodologies.

Liliana J G Silva et al.

Foods (Basel, Switzerland), 10(1) (2020-12-31)

Citrinin (CIT) deserves attention due to its known toxic effects in mammalian species and its widespread occurrence in food commodities, often along with ochratoxin A, another nephrotoxic mycotoxin. Human exposure, a key element in assessing risk related to food contaminants

Effect of dissolved oxygen concentration on red pigment and citrinin production by Monascus purpureus ATCC 36928

Brazilian Journal of Chemical Engineering, 25, 247-253 (2008)

Low occurrence of patulin- and citrinin-producing species isolated from grapes.

M R Bragulat et al.

Letters in applied microbiology, 47(4), 286-289 (2009-02-26)

To assess the ability of fungi isolated from grapes to produce patulin and citrinin. A total of 446 Aspergillus isolates belonging to 20 species and 101 Penicillium isolates were inoculated in Czapek yeast extract agar and yeast extract sucrose agar

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