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Merck

D3759

Dextrano from Leuconostoc mesenteroides

average mol wt 48,000-90,000

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Fórmula lineal:
(C6H10O5)n
Número CAS:
UNSPSC Code:
12352201
NACRES:
NA.25
EC Number:
232-677-5
MDL number:
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Nombre del producto

Dextrano from Leuconostoc mesenteroides, average mol wt 48,000-90,000

SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

biological source

bacterial (Leuconostoc mesenteroides)

form

powder

optical activity

[α]/D 199°

mol wt

average mol wt 48,000-90,000

color

white

solubility

H2O: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

Quality Level

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Application

El uso de dextranos como brazos espaciadores largos e hidrófilos mejora el rendimiento de las proteínas inmovilizadas que actúan sobre las macromoléculas.
Dextrans are used in many applications as platelet aggregants, plasma volume extenders, osmotic pressure regulators, stabilizers, organ separation media, matrix components, copolymers, microcarriers, binding agents, viscosity modifiers, antithrombotics, lubricants and physical structure components. They may be used as long hydrophilic spacer arms to improve the performance (freedom of movement) of conjugated/bound proteins. Dextrans may be derivatized for use in biosensor systems.
Dextrans of less than 60,000Da are generally considered low molecular weight dextrans. Low molecular weight dextrans are often preferred versus high molecular weight dextrans due to their viscosities, aggregation and permeation properties. High molecular weight, water-soluble, dextran polymers have been used in a wide variety of biomedical applications. Dextran (48,000-90,000) may be used to induce blood aggregation and as a viscosity plasma expander (HVPE).

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Leena Pitkänen et al.
Investigative ophthalmology & visual science, 46(2), 641-646 (2005-01-27)
To determine the effects of solute molecular weight and lipophilicity on the permeability of a retinal pigment epithelium (RPE)-choroid preparation. Fresh RPE-choroid specimens from bovine eyes were placed in diffusion chambers for permeability experiments with carboxyfluorescein, fluorescein isothiocyanate (FITC)-labeled dextrans
Sahitya Katikaneni et al.
Bioanalysis, 3(21), 2419-2426 (2011-11-15)
The purpose of this study was to optimize parameters pertaining to microdialysis technique so as to make this method feasible for evaluating transdermal transport of macromolecules. Microdialysis experiments were performed in vivo using hairless rats with daniplestim as the model
Andreas M A O Pollet et al.
Micromachines, 11(1) (2020-01-08)
The vasculature plays a central role as the highway of the body, through which nutrients and oxygen as well as biochemical factors and signals are distributed by blood flow. Therefore, understanding the flow and distribution of particles inside the vasculature
Molecular Weight Effects on the Miscibility Behavior of Dextran and Maltodextrin with Poly(vinylpyrrolidone).
Van Eerdenbrugh B, Taylor LS.
Pharmaceut. Res., doi: 10-doi: 10 (2012)
Yuichi Ozaki et al.
Circulation journal : official journal of the Japanese Circulation Society, 76(4), 922-927 (2012-02-04)
Although an intracoronary frequency-domain optical coherence tomography (FD-OCT) system overcomes several limitations of the time-domain OCT (TD-OCT) system, the former requires injection of contrast media for image acquisition. The increased total amount of contrast media for FD-OCT image acquisition may

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