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H1635

N-Hippuryl-His-Leu hydrate

chromogenic, ≥98% (HPLC), powder

Sinónimos:

N-Benzoyl-Gly-His-Leu, N-Hippuryl-L-histidyl-L-leucine hydrate

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Fórmula empírica (notación de Hill):
C21H27N5O5 · xH2O
Número CAS:
207386-83-2
Peso molecular:
429.47 (anhydrous basis)
NACRES:
NA.32
PubChem Substance ID:
24895469
UNSPSC Code:
12352204
EC Number:
250-597-9
MDL number:
MFCD00149318
Beilstein/REAXYS Number:
5664178
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Nombre del producto

N-Hippuryl-His-Leu hydrate, powder, ≥98% (HPLC)

Quality Level

200

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

acetic acid: ~50 mg/mL

storage temp.

−20°C

SMILES string

O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O

InChI

1S/C21H27N5O5.H2O/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H2/t16-,17-;/m0./s1

InChI key

NWOJMNXIJBZMPK-QJHJCNPRSA-N

Gene Information

human ... ACE(1636), ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421), ACE2(70008), ACE3(498012)

General description

Substrate for angiotensin converting enzyme.

Application

N-Hippuryl-His-Leu hydrate has been used in the measurement of angiotensin-converting enzyme (ACE) inhibitory activity using oyster hydrolysates, semimembranosus muscle samples, and rabbit lung acetone powder.

Biochem/physiol Actions

N-Hippuryl-His-Leu hydrate (HHL) can be used as an artificial substrate for angiotensin-converting enzyme (ACE).

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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000506150
0000506150
0000506157
0000506157
0000506156

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