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I1896

Interleukin-13 from mouse

Name: Interleukin-13 from mouse
Brand: SIGMA

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Sinónimos:

IL-13

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UNSPSC Code:

12352202

NACRES:

NA.32

MDL number:

MFCD00675503

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Propiedades

biological source

mouse

Quality Segment

100

recombinant

expressed in E. coli

assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

1-10 ng/mL EC₅₀

mol wt

11.5 kDa (predicted; 9 kDa under reducing conditions)

packaging

pkg of 5 μg

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

P20109

storage temp.

−20°C

Gene Information

mouse ... Il13(16163)

Descripción

Biochem/physiol Actions

Interleukin-13 is a pleiotropic cytokine produced by activated Th2 cells in the mouse and human. IL-13 is secreted mainly as an unglycosylated protein of 132 amino acids with a molecular weight of 10,000 daltons. A 4.3kb DNA fragment of the mouse IL-13 gene was sequenced and occurs as a single copy mapping a chromosome 11. In the human, a 4.6 kb DNA segment of the IL-13 gene occurs as a single copy and maps to chromosome 5. IL-13 induces B cell proliferation and also induces IgE switching. The proliferative activity of human and mouse IL-13 products are tested in culture using the human erythroleukemic cell line TF-1.

Physical form

lyophilized from a 0.2 μm filtered solution in phosphate buffered saline (PBS), pH 7.4, with 50 μg bovine serum albumin (BSA) per 1 μg of cytokine

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c