M8574

D-(+)-Manosa

Name: <SC>D</SC>-(+)-Manosa
Brand: SIGMA

synthetic, ≥99% (GC)

Sinónimos:

D-mannopiranosa

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About This Item

Fórmula empírica (notación de Hill):

C₆H₁₂O₆

Número CAS:

3458-28-4

Peso molecular:

180.16

UNSPSC Code:

12352201

NACRES:

NA.25

PubChem Substance ID:

329818064

EC Number:

222-392-4

Beilstein/REAXYS Number:

1564373

MDL number:

MFCD00064122

Nombre del producto

D-(+)-Manosa, synthetic, ≥99% (GC)

InChI key

WQZGKKKJIJFFOK-QTVWNMPRSA-N

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1

SMILES string

OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O

biological source

synthetic

assay

≥99% (GC)

form

powder

optical activity

[α]25/D 13.5 to 14.9 °, c = 4% (w/v) in water

technique(s)

gas chromatography (GC): suitable

color

white to off-white

mp

133-140 °C (lit.)

solubility

water: soluble 10 g/L at 20 °C

storage temp.

room temp

Quality Level

200

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Categorías relacionadas

Biología química

Suplementos y reactivos para cultivo celular

Application

D-(+)-Mannose, a C-2 epimer of D-glucose, is used in the formation of glycan structure and glycosylation.

Biochem/physiol Actions

Mannose, a six-carbon carbohydrate, is the C-2 epimer of glucose and a critical sugar for protein glycosylation. Mannose can also be utilized by the brain as an alternative energy source.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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D-mannose suppresses macrophage IL-1β production.

Simone Torretta et al.

Nature communications, 11(1), 6343-6343 (2020-12-15)

D-mannose is a monosaccharide approximately a hundred times less abundant than glucose in human blood. Previous studies demonstrated that supraphysiological levels of D-mannose inhibit tumour growth and stimulate regulatory T cell differentiation. It is not known whether D-mannose metabolism affects

Impact of asymptomatic herpes simplex virus type 2 infection on mucosal homing and immune cell subsets in the blood and female genital tract.

Brett Shannon et al.

Journal of immunology (Baltimore, Md. : 1950), 192(11), 5074-5082 (2014-04-25)

HSV-2 infection is common and generally asymptomatic, but it is associated with increased HIV susceptibility and disease progression. This may relate to herpes-mediated changes in genital and systemic immunology. Cervical cytobrushes and blood were collected from HIV-uninfected African/Caribbean women in

Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy.

Charles D Murin et al.

Journal of virology, 88(17), 10177-10188 (2014-06-27)

The neutralizing anti-HIV-1 antibody 2G12 is of particular interest due to the sterilizing protection it provides from viral challenge in animal models. 2G12 is a unique, domain-exchanged antibody that binds exclusively to conserved N-linked glycans that form the high-mannose patch

A set of powerful negative selection systems for unmodified Enterobacteriaceae.

Varnica Khetrapal et al.

Nucleic acids research, 43(13), e83-e83 (2015-03-25)

Creation of defined genetic mutations is a powerful method for dissecting mechanisms of bacterial disease; however, many genetic tools are only developed for laboratory strains. We have designed a modular and general negative selection strategy based on inducible toxins that

High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium.

Cecilia W Huo et al.

Breast cancer research : BCR, 17, 79-79 (2015-06-05)

Mammographic density (MD), after adjustment for a women's age and body mass index, is a strong and independent risk factor for breast cancer (BC). Although the BC risk attributable to increased MD is significant in healthy women, the biological basis

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