N183
NBQX disodium salt hydrate
≥98% (HPLC), lyophilized powder, neuroprotective AMPA/kainate glutamate receptor antagonist
Sinónimos:
1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium salt hydrate, FG 9202 disodium salt hydrate
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Nombre del producto
NBQX disodium salt hydrate, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
lyophilized powder
storage condition
desiccated
color
, brown to dark red-brown
solubility
H2O: >10 mg/mL
storage temp.
2-8°C
SMILES string
O.[Na+].[Na+].NS(=O)(=O)c1cccc2c1c(cc3nc([O-])c([O-])nc23)[N+]([O-])=O
InChI
1S/C12H8N4O6S.2Na.H2O/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6;;;/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22);;;1H2/q;2*+1;/p-2
InChI key
LQSCHRKYVVVUFA-UHFFFAOYSA-L
Gene Information
human ... GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893), GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK4(2900), GRIK5(2901)
Application
- in N-methyl-D-aspartate receptor (NMDAR) kinetic studies
- as an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist for the electrophysiological studies cultured neurons
- in the extracellular solution for current/voltage (I/V) relationship and rectification index experiments in excitatory postsynaptic currents (EPSCs) mediated by NMDA receptors (EPSCNMDAR)
Biochem/physiol Actions
Features and Benefits
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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