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Merck

P6777

Phenelzine sulfate salt

synthetic, ≥98% (iodine, titration), MAO-A/B inhibitor, powder

Sinónimos:

Phenelzine hydrogen sulphate

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Fórmula empírica (notación de Hill):
C8H12N2 · H2O4S
Número CAS:
156-51-4
Peso molecular:
234.27
NACRES:
NA.77
PubChem Substance ID:
24278646
UNSPSC Code:
12352200
EC Number:
205-856-0
MDL number:
MFCD00050687
Assay:
≥98% (iodine, titration)
Form:
powder
Quality level:
200

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Nombre del producto

Phenelzine sulfate salt,

InChI key

RXBKMJIPNDOHFR-UHFFFAOYSA-N

InChI

1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)

SMILES string

NNCCC1=CC=CC=C1.OS(=O)(O)=O

biological source

synthetic

assay

≥98% (iodine, titration)

form

powder

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

Quality Level

200

Gene Information

human ... MAOA(4128), MAOB(4129)

Categorías relacionadas

Biochem/physiol Actions

Non-selective MAO-A/B inhibitor.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
BCCK9477
BCCK4308
BCCG9192
BCBN9644V
BCBX0084

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Adeline Su-Yin Ngo et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 6(4), 431-434 (2010-07-24)
Phenelzine is an irreversible monoamine oxidase inhibitor (MAOI). Hypertensive reactions after ingestion of tyramine-rich foods such as cheese are well known. However, a review of the available medical literature found no previous reports of myocardial infarction resulting from the ingestion
Marco De Giovanni et al.
Science immunology, 9(93), eadj7363-eadj7363 (2024-03-01)
Peyer's patches (PPs) are lymphoid structures situated adjacent to the intestinal epithelium that support B cell responses that give rise to many intestinal IgA-secreting cells. Induction of isotype switching to IgA in PPs requires interactions between B cells and TGFβ-activating
Travis Musgrave et al.
Brain, behavior, and immunity, 25(8), 1677-1688 (2011-07-05)
Multiple sclerosis (MS) and the animal model, experimental autoimmune encephalomyelitis (EAE), are both accompanied by motor and non-motor symptoms. Pathological changes in the activities of key neurotransmitters likely underlie many of these symptoms. We have previously described disturbances in the
Ghulam Abbas et al.
Phytotherapy research : PTR, 27(1), 39-45 (2012-03-27)
The current study was aimed at investigating the potential antidepressant activity of Areca catechu nut ethanol extract and its various fractions using behavioral (acute and sub-chronic forced swim tests) and biochemical (monoamines and their metabolite levels using high performance liquid
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