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R3250

Acetato de retinil

Name: Acetato de retinil
Brand: SIGMA

synthetic, matrix dispersion, 475,000-650,000 USP units/g

Sinónimos:

Acetato de retinol, Acetato de vitamina A

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Fórmula empírica (notación de Hill):

C₂₂H₃₂O₂

Número CAS:

127-47-9

Peso molecular:

328.49

NACRES:

NA.79

PubChem Substance ID:

57654589

eCl@ss:

34058009

UNSPSC Code:

12352205

EC Number:

204-844-2

MDL number:

MFCD00019413

Beilstein/REAXYS Number:

1915439

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Propiedades

biological source

synthetic

Quality Segment

200

form

matrix dispersion

specific activity

475,000-650,000 USP units/g

color

yellow

mp

57-58 °C

storage temp.

−20°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

Descripción

General description

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate.

Application

Retinyl acetate has been used:

a control diet to study its effect at different developmental periods in fish larvae
to study its inhibitory effects on Mycobacterium avium subspecies paratuberculosis (MAP) strains
as an internal standard in high performance liquid chromatography (HPLC) to quantify vitamin A in fortified milk

Biochem/physiol Actions

Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as required. Retinyl acetate is used in a wide range of biological applications. It acts as a chemopreventive agent. Retinyl acetate also has antineoplastic property.

Physical form

Dispersion in cornstarch-gelatin matrix. Oil dispersible

Analysis Note

Activity based on HPLC comparison to USP standard.

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pictograms

GHS08

signalword

Danger

hcodes

H360D,H413

pcodes

P202 - P273 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c