RAB0057

Rat MCP-1 / CCL2 ELISA Kit

Name: Rat MCP-1 / CCL2 ELISA Kit
Brand: SIGMA

for serum, plasma and cell culture supernatant

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About This Item

NACRES:

NA.32

UNSPSC Code:

41116158

Nombre del producto

Rat MCP-1 / CCL2 ELISA Kit, for serum, plasma and cell culture supernatant

species reactivity

rat

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 15 pg/mL
standard curve range: 24.67-18000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

rat ... Ccl2(24770)

Categorías relacionadas

Enzyme-Linked Immunosorbent Assay (ELISA) Kits

Immunoassay Platform Solutions

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

General description

The Rat MCP-1 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of rat MCP-1 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Rat MCP1

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

pictograms

GHS05

signalword

Warning

hcodes

H290

pcodes

P234 - P390

Hazard Classifications

Met. Corr. 1

Clase de almacenamiento

8A - Combustible corrosive hazardous materials

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CCL2 mediates early renal leukocyte infiltration during salt-sensitive hypertension.

Ammar J Alsheikh et al.

American journal of physiology. Renal physiology, 318(4), F982-F993 (2020-03-10)

Studies examining mechanisms of Dahl salt-sensitive (SS) hypertension have implicated the infiltration of leukocytes in the kidneys, which contribute to renal disease and elevated blood pressure. However, the signaling pathways by which leukocytes traffic to the kidneys remain poorly understood.

Effects of Saskatoon berry powder on monocyte adhesion to vascular wall of leptin receptor-deficient diabetic mice.

Ruozhi Zhao et al.

The Journal of nutritional biochemistry, 25(8), 851-857 (2014-06-14)

Atherosclerotic cardiovascular complications are the leading cause of death in diabetic patients. Monocyte adhesion is an early event for atherogenesis. Previous studies demonstrated that dark-skin berries had cardiovascular protective effects. We hypothesize that Saskatoon berry (SB) powder may reduce monocyte

Mutant monocyte chemoattractant protein 1 protein attenuates migration of and inflammatory cytokine release by macrophages exposed to orthopedic implant wear particles.

Zhenyu Yao et al.

Journal of biomedical materials research. Part A, 102(9), 3291-3297 (2013-10-15)

Wear particles generated from total joint replacements can stimulate macrophages to release chemokines, such as monocyte chemoattractant protein 1 (MCP-1), which is the most important chemokine regulating systemic and local cell trafficking and infiltration of monocyte/macrophages in chronic inflammation. One

No Impairment in host defense against Streptococcus pneumoniae in obese CPEfat/fat mice.

Peter Mancuso et al.

PloS one, 9(9), e106420-e106420 (2014-09-10)

In the US and globally, dramatic increases in the prevalence of adult and childhood obesity have been reported during the last 30 years. In addition to cardiovascular disease, type II diabetes, and liver disease, obesity has recently been recognized as

Pulmonary venous hypertension and mechanical strain stimulate monocyte chemoattractant protein-1 release and structural remodelling of the lung in human and rodent chronic heart failure models.

John E S Park et al.

Thorax, 69(12), 1120-1127 (2014-09-17)

The burden of chronic heart failure (HF) is rising owing to an increased survivorship after myocardial infarction (MI). Pulmonary structural remodelling in patients with HF may protect against oedema while causing dyspnoea, the predominant symptom associated with HF. The cellular

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Contenido relacionado

User Guide-RAB0057

ELISA Kit Information

Instructions