S1402
Sulforhodamine B sodium salt
powder, BioReagent, suitable for cell culture
Sinónimos:
Kiton Red 620
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Fórmula empírica (notación de Hill):
C27H29N2NaO7S2
Número CAS:
Peso molecular:
580.65
EC Number:
222-529-8
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
MDL number:
Colour Index Number:
45100
Beilstein/REAXYS Number:
3886008
Servicio técnico
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Permítanos ayudarlebiological source
synthetic (organic)
Quality Level
product line
BioReagent
form
powder
composition
Dye content, ~75%
technique(s)
cell culture | mammalian: suitable
solubility
methanol: 1 mg/mL
fluorescence
λex 565 nm; λem 586 nm in H2O
SMILES string
[Na+].CCN(CC)c1ccc2c(OC3=CC(\C=CC3=C2c4ccc(cc4S([O-])(=O)=O)S([O-])(=O)=O)=[N+](\CC)CC)c1
InChI
1S/C27H30N2O7S2.Na/c1-5-28(6-2)18-9-12-21-24(15-18)36-25-16-19(29(7-3)8-4)10-13-22(25)27(21)23-14-11-20(37(30,31)32)17-26(23)38(33,34)35;/h9-17H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1
InChI key
SXQCTESRRZBPHJ-UHFFFAOYSA-M
General description
Sulforhodamine B is a rhodamine derived aminoxanthene dye. It contains two sulfonic acids groups which separate in alkaline condition.
Application
Sulforhodamine B sodium salt has been used:
- for relative total cell mass quantification
- to investigate the viscosity of coacervates
- as a molecular rotor for microviscosity determination in aerosol droplets
Biochem/physiol Actions
Sulforhodamine B sodium salt is useful to measure cell biomass and also for cytotoxicity screening.
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation (2012)
Bioconjugate Techniques, 317-317 (1996)
Luca Giordano et al.
American journal of respiratory cell and molecular biology, 60(5), 515-522 (2018-10-20)
Cigarette smoke (CS) exposure is the predominant risk factor for the development of chronic obstructive pulmonary disease (COPD) and the third leading cause of death worldwide. We aimed to elucidate whether mitochondrial respiratory inhibition and oxidative stress are triggers in