U6625
Uridine 5′-triphosphate trisodium salt hydrate
From yeast, ≥96%, P2Y receptor agonist
Sinónimos:
UTP Na3
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Fórmula empírica (notación de Hill):
C9H12N2Na3O15P3 · xH2O
Número CAS:
Peso molecular:
550.09 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
3585234
Assay:
≥96%
Quality level:
Servicio técnico
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Permítanos ayudarleNombre del producto
Uridine 5′-triphosphate trisodium salt hydrate, from yeast, Type III, ≥96%
biological source
yeast
Quality Level
type
Type III
assay
≥96%
solubility
H2O: soluble 50 mg/mL, clear to slightly hazy, colorless
shipped in
dry ice
storage temp.
−20°C
SMILES string
[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
InChI
1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
InChI key
MMJGIWFJVDOPJF-LLWADOMFSA-K
Application
UTP has been used to study its vasodilatory effects on the skeletal muscle cells of diabetic patients. UTP has also been used as a purinergic agonist to study ion transport functions of P2Y2 receptors on rat basolateral membranes.
Biochem/physiol Actions
P2Y receptor agonist.
Preparation Note
Uridine 5′-triphosphate trisodium salt (UTP Na3) hydrate dissolves in water at 50 mg/ml to yield a clear to slightly hazy, colorless solution.
Clase de almacenamiento
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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O-GlcNAcylation is a post-translational modification catalysed by O-GlcNAc transferase (OGT). Missense mutations in OGT have been associated with developmental disorders, OGT-linked congenital disorder of glycosylation (OGT-CDG), which are characterized by intellectual disability. OGT relies on the hexosamine biosynthetic pathway (HBP)
Alexander Puzenko et al.
The Journal of chemical physics, 137(19), 194502-194502 (2012-11-28)
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