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Merck

1601827

USP

Trichloroethylene solution

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Trichloroethylene solution, Trichloroethene

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Número CAS:
79-01-6
MDL number:
MFCD00000838
UNSPSC Code:
41116107
EC Number:
201-167-4
NACRES:
NA.24

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Nombre del producto

Trichloroethylene solution, United States Pharmacopeia (USP) Reference Standard

SMILES string

ClC(=CCl)Cl

InChI key

XSTXAVWGXDQKEL-UHFFFAOYSA-N

InChI

1S/C2HCl3/c3-1-2(4)5/h1H

grade

pharmaceutical primary standard

form

solution

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

single component solution

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Residual Solvent Class 2 - Trichloroethylene USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

General description

This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Central nervous system

Clase de almacenamiento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

closed cup - does not flash

flash_point_c

closed cup - does not flash

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Lot/Batch Number

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Glinda S Cooper et al.
Environmental health perspectives, 117(5), 696-702 (2009-05-30)
Our objective was to examine experimental and epidemiologic studies pertaining to immune-related, and specifically autoimmune-related, effects of trichloroethylene (TCE). We performed a literature search of PubMed and reviewed bibliographies in identified articles. We then systematically reviewed immune-related data, focusing on
David J Jollow et al.
Critical reviews in toxicology, 39(9), 782-797 (2009-10-27)
Trichloroethylene (TCE) is a widespread environmental contaminant that is carcinogenic when given in high, chronic doses to certain strains of mice and rats. The capacity of TCE to cause cancer in humans is less clear. The current maximum contaminant level
Dominik D Alexander et al.
International archives of occupational and environmental health, 81(2), 127-143 (2007-05-12)
Findings from epidemiologic studies of trichloroethylene (TCE) exposure and liver cancer have been inconsistent. To quantitatively evaluate this association and to examine sources of heterogeneity, we conducted a meta-analysis of occupational studies of TCE exposure and liver/biliary tract cancer. We
Michihiro Kamijima et al.
International archives of occupational and environmental health, 80(5), 357-370 (2006-11-16)
Workers exposed to trichloroethylene (TCE) rarely show severe generalized skin disorders and accompanying hepatitis which resemble drug hypersensitivities. The disorders are completely different from solvent-induced irritating contact dermatitis, and their serious consequences have become one of the critical occupational health
Fariha Zaheer et al.
Neurologic clinics, 29(3), 657-665 (2011-08-02)
Multiple genetic and environmental etiologies have been implicated in the pathogenesis of idiopathic Parkinson disease. Recent observations have suggested an association between chronic exposure to trichloroethylene (TCE) and development of clinical parkinsonism. Animal models of TCE exposure have shown nigrostriatal
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