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Merck

1672745

USP

Tranexamic acid

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

trans-4-(Aminomethyl)cyclohexanecarboxylic acid, AMCA, AMCHA, HAKU, TAMCHA, Tranexamic acid

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Fórmula lineal:
H2NCH2C6H10CO2H
Número CAS:
1197-18-8
Peso molecular:
157.21
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329751362
MDL number:
MFCD00001466
Beilstein/REAXYS Number:
2207452

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Nombre del producto

Tranexamic acid, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-

SMILES string

NC[C@H]1CC[C@@H](CC1)C(O)=O

InChI key

GYDJEQRTZSCIOI-LJGSYFOKSA-N

grade

pharmaceutical primary standard

API family

tranexamic acid

manufacturer/tradename

USP

mp

>300 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... PLG(5340)

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Tranexamic acid USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Tranexamic Acid Tablets
  • Tranexamic Acid Injection

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Chee Ching Chan et al.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 270(2), 735-748 (2012-09-22)
Post-tonsillectomy haemorrhage is a serious complication that can lead to death despite the fact that tonsillectomy is one of the commonest procedures performed in otolaryngology. Post-operative haemorrhage can be reduced by a potent antifibrinolytic agent such as tranexamic acid (TXA).
Tranexamic acid in trauma: how should we use it?
Lena M Napolitano et al.
The journal of trauma and acute care surgery, 74(6), 1575-1586 (2013-05-23)
Anshul Dahuja et al.
The Journal of arthroplasty, 29(4), 733-735 (2013-11-05)
Total knee arthroplasty(TKA) is associated with extensive postoperative blood loss. Despite various studies proving the efficacy of Tranexamic Acid (TEA) with single or multiple boluses of different sizes with or without subsequent infusions, no consensus has been reached on the
Joseph G Martin et al.
The Journal of arthroplasty, 29(5), 889-894 (2013-11-19)
Major blood loss is a known potential complication in total hip and total knee arthroplasty. We conducted a prospective, stratified, randomized, double-blind, placebo-controlled trial that evaluated 100 patients undergoing total knee or total hip arthroplasty to evaluate the effect on
Julian Gilbody et al.
The Journal of arthroplasty, 29(4), 681-684 (2013-10-08)
The efficaciousness of topical tranexamic acid use at the end of knee arthroplasty surgery to reduce blood loss and transfusion requirements has previously been shown. The aim of this study was to retrospectively assess the effectiveness of topical tranexamic acid
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