364959
N-[Tris(hydroxymethyl)methyl]acrylamide
contains ≤7% KCl, 93%
Synonym(s):
NAT, TRIS-acrylamide
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About This Item
Linear Formula:
H2C=CHCONHC(CH2OH)3
CAS Number:
Molecular Weight:
175.18
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
237-645-4
Beilstein/REAXYS Number:
2081162
MDL number:
Quality Level
assay
93%
form
solid
contains
≤7% KCl
mp
136-141 °C (lit.)
storage temp.
2-8°C
SMILES string
OCC(CO)(CO)NC(=O)C=C
InChI
1S/C7H13NO4/c1-2-6(12)8-7(3-9,4-10)5-11/h2,9-11H,1,3-5H2,(H,8,12)
InChI key
MVBJSQCJPSRKSW-UHFFFAOYSA-N
Application
- Reactions of dipropilamine with unsaturated surfactants in the model oil–water system: This study investigates the reactions of dipropilamine with N-[tris(hydroxymethyl)methyl]acrylamide, highlighting potential applications in industrial and pharmaceutical processes (Simonian, 2015).
- Water-dispersible polymer coated silica nanoparticle for turn-on fluorometric detection of Cephalexin: Utilizes N-[Tris(hydroxymethyl)methyl]acrylamide in the synthesis of a polymer to improve the detection capabilities for pharmaceutical applications, showcasing the adaptability of this monomer in enhancing sensor technologies (Sahu et al., 2022).
- Ultrasound-triggered piezocatalytic composite hydrogels for promoting bacterial-infected wound healing: Features a hydrogel based on N-[tris(hydroxymethyl)methyl]acrylamide for medical applications, particularly in accelerating wound healing, which is crucial for drug delivery systems and tissue engineering (Liu et al., 2023).
- An adhesive and resilient hydrogel for the sealing and treatment of gastric perforation: Describes the development of a hydrogel incorporating N-[tris(hydroxymethyl)methyl]acrylamide for potential medical use in treating internal wounds, demonstrating the material′s medical applications in a clinical setting (Webb et al., 2022).
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Kourosh Zarringhalam et al.
Scientific reports, 7(1), 7755-7755 (2017-08-12)
Regulation by microRNAs (miRNAs) and modulation of miRNA activity are critical components of diverse cellular processes. Recent research has shown that miRNA-based regulation of the tumor suppressor gene PTEN can be modulated by the expression of other miRNA targets acting
Anthony C Cruz et al.
Nature communications, 7, 13895-13895 (2016-12-23)
Mutations affecting the apoptosis-inducing function of the Fas/CD95 TNF-family receptor result in autoimmune and lymphoproliferative disease. However, Fas can also costimulate T-cell activation and promote tumour cell growth and metastasis. Palmitoylation at a membrane proximal cysteine residue enables Fas to
Ashish C Shrestha et al.
Transfusion, 56(12), 3086-3093 (2016-10-21)
Hepatitis E virus (HEV) poses a risk to transfusion safety. In Australia, locally acquired HEV is rare and cases are mainly reported in travelers returning from countries endemic for HEV. The risk posed by HEV to transfusion safety in Australia