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Merck

T32603

2-Thiophenecarboxylic acid

ReagentPlus®, 99%

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About This Item

Empirical Formula (Hill Notation):
C5H4O2S
CAS Number:
Molecular Weight:
128.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-423-4
Beilstein/REAXYS Number:
110150
MDL number:
Assay:
99%
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Quality Level

product line

ReagentPlus®

assay

99%

bp

260 °C (lit.)

mp

125-127 °C (lit.)

SMILES string

OC(=O)c1cccs1

InChI

1S/C5H4O2S/c6-5(7)4-2-1-3-8-4/h1-3H,(H,6,7)

InChI key

QERYCTSHXKAMIS-UHFFFAOYSA-N

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Laval Chan et al.
Bioorganic & medicinal chemistry letters, 14(3), 797-800 (2004-01-27)
Further SAR studies on the thiophene-2-carboxylic acids are reported. These studies led to the identification of a series of tertiary amides that show inhibition of both HCV NS5B polymerase in vitro and HCV subgenomic RNA replication in Huh-7 cells. Structural
C Savarin et al.
Organic letters, 3(14), 2149-2152 (2001-07-07)
[reaction: see text] A new protocol for the palladium-catalyzed, copper-mediated coupling of aryl and alkenyl iodides with boronic acids is described. As an alternative to the well-known and widely used Suzuki cross-coupling, this reaction occurs in the absence of a
Hao Li et al.
Organic letters, 13(14), 3682-3685 (2011-06-17)
A stereocontrolled synthesis of α-amino-α'-alkoxy ketones is described. This pH-neutral copper(I) thiophene-2-carboxylate (CuTC)-catalyzed cross-coupling of amino acid thiol esters and chiral nonracemic α-alkoxyalkylstannanes gives α-amino-α'-alkoxy ketones in good to excellent yields with complete retention of configuration at the α-amino- and