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PHR1161

Procaine hydrochloride

Name: Procaine hydrochloride
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

4-Aminobenzoic acid 2-diethylaminoethyl ester, p-Aminobenzoic acid diethylaminoethyl ester hydrochloride, Novocaine hydrochloride

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About This Item

Linear Formula:

H₂NC₆H₄CO₂CH₂CH₂N(C₂H₅)₂·HCl

CAS Number:

51-05-8

Molecular Weight:

272.77

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823178

EC Number:

200-077-2

Beilstein/REAXYS Number:

3917802

MDL number:

MFCD00013000

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Properties

Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1564006

API family

procaine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

155-156 °C (lit.)

application(s)

pharmaceutical (small molecule)
pharmaceutical

format

neat

storage temp.

2-30°C

SMILES string

Cl.CCN(CC)CCOC(=O)c1ccc(N)cc1

InChI

1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H

InChI key

HCBIBCJNVBAKAB-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Description

General description

Procaine hydrochloride is a synthetic compound that belongs to the class of local anesthetic drugs. It has a structure similar to the natural compounds that participate in nerve impulse transmission. It shows interaction with the cellular membranes causing membrane lipids to expand, membrane-bound calcium to displace and change the structure of the proteins that are responsible for regulating the cell permeability and shape.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Procaine hydrochloride can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrochemical, chemiluminescence, and spectrophotometric techniques.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA7177 in the slot below. This is an example certificate only and may not be the lot that you receive.

Values of analytes vary lot to lot.

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Pictograms

GHS06

Signal Word

Danger

Hazard Codes

H301,H317

Precautionary Statements

P261 - P264 - P270 - P280 - P301 + P310 - P302 + P352

Hazard Classifications

Acute Tox. 3 Oral - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)