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B6929

Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt

≥95%

Synonym(s):

des(Arg10, Leu9)-Kallidin

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About This Item

Empirical Formula (Hill Notation):
C47H75N13O11
Molecular Weight:
998.18
NACRES:
NA.32
PubChem Substance ID:
329773287
UNSPSC Code:
12352203
MDL number:
MFCD00274007
Assay:
≥95%
Form:
powder
Quality level:
200
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Quality Level

200

assay

≥95%

form

powder

storage temp.

−20°C

SMILES string

CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCCN)C(O)=O

InChI

1S/C47H75N13O11/c1-28(2)24-33(46(70)71)56-42(66)36-17-10-21-58(36)44(68)34(27-61)57-40(64)32(25-29-12-4-3-5-13-29)54-38(62)26-53-41(65)35-16-9-22-59(35)45(69)37-18-11-23-60(37)43(67)31(15-8-20-52-47(50)51)55-39(63)30(49)14-6-7-19-48/h3-5,12-13,28,30-37,61H,6-11,14-27,48-49H2,1-2H3,(H,53,65)(H,54,62)(H,55,63)(H,56,66)(H,57,64)(H,70,71)(H4,50,51,52)/t30-,31-,32-,33-,34-,35-,36-,37-/m0/s1

InChI key

AGTPZUQKOYEAOH-MDKUUQCZSA-N

Gene Information

human ... BDKRB1(623)
mouse ... BDKRB1(12061)
rat ... BDKRB1(81509)

Biochem/physiol Actions

B1 bradykinin receptor antagonist.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG3832
BCBZ2878
BCBM1666V
BCBJ0208V
BCBG5097V

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S P Zhang et al.
Life sciences, 62(25), 2303-2314 (1998-07-03)
Bradykinin (BK) receptors are involved in pain and inflammation. Two BK receptor subtypes, B1 and B2, have been defined based on their pharmacological properties. Both B1 and B2 receptors are G-protein coupled membrane receptors. B1 receptors are present in smooth
T MacNeil et al.
Canadian journal of physiology and pharmacology, 75(6), 735-740 (1997-06-01)
We developed a functional assay to evaluate the activity of kinin peptides at the human and mouse bradykinin (BK) B1 receptors. The photoprotein aequorin expressed in 293-AEQ17 cells was used to measure calcium mobilization due to activation of the human
J G Menke et al.
The Journal of biological chemistry, 269(34), 21583-21586 (1994-08-26)
A cDNA clone encoding a human B1 bradykinin receptor was isolated from a human embryonic lung fibroblast cDNA library by expression cloning. The photoprotein aequorin was utilized as an indicator of the ability of the B1 receptor agonist [des-Arg10]kallidin to
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