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EHU065221

MISSION® esiRNA

targeting human ARAP1

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GAGGACGAGGAGGAGAAGGTCTCCAGGTACCGAGAGCTGCTGGTGCGGCTGCCCCCTGTCAACCGGGCCACAGTGAAGGCCCTTATCAGCCACCTGTACTGTGTTCAGTGCTTCTCAGACACGAACCAGATGAACGTGCACAACCTGGCAATTGTGTTTGGGCCCACGCTCTTCCAGACAGATGGGCAGGACTACAAGGCTGGCCGTGTGGTGGAAGACCTCATTAACCACTATGTGGTGGTGTTTAGTGTGGATGAGGAAGAGCTCAGGAAGCAGCGGGAGGAGATCACTGCCATTGTGAAGATGCGCGTGGCTGGCACTGCCAGTGGGACCCAGCATGCCGGTGACTTCATCTGCACAGTGTATCTGGAAGAGAAGAAGGCAGAGACTGAGCAGCATATCAAGGTCCCAGCAT

Ensembl | human accession no.

ENSG00000186635

NCBI accession no.

NM_015242

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... ARAP1(116985)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Lulu Li et al.
Journal of cellular physiology, 235(7-8), 5787-5795 (2020-01-25)
The epithelial-mesenchymal transition (EMT) plays an important role in diabetic renal fibrosis. The ARAP1 gene is located near risk alleles for Type 2 diabetes, and its function has been linked to cytoskeleton rearrangement, Golgi apparatus remodeling, and endocytic trafficking of