H0915
Hydroxychloroquine sulfate
≥98% (HPLC), powder, anti-inflammatory
Synonym(s):
Hydroxychloroquine sulfate, 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate
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About This Item
Product Name
Hydroxychloroquine sulfate, ≥98% (HPLC), powder
Quality Level
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white to off-white
solubility
H2O: >20 mg/mL
SMILES string
OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
InChI
1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
InChI key
JCBIVZZPXRZKTI-UHFFFAOYSA-N
Gene Information
human ... TLR7(51284), TLR9(54106)
Application
- as an inhibitor of autophagy to treat cells for apoptosis assay to study the role of pirarubicin induced autophagy in bladder cancer cell line
- to evaluate the antiviral mechanism of hydroxychloroquine against DENV-2 (dengue virus-2) infection by immunofluorescence assay
- to inhibit lysosome fusion with the autophagosome
Biochem/physiol Actions
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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