RAB0642
Human F3 / Tissue Factor ELISA Kit
Synonym(s):
Coagulation factor III, TF, Thromboplastin, Tissue factor
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... F3(2152)
Input:
sample type cell culture supernatant(s)
sample type serum
sample type plasma
sample type serum
sample type plasma
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 6 pg/mL
standard curve range: 6.14-1500 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... F3(2152)
General description
The antibody pair provided in this kit recognizes human Coagulation Factor III/Tissue Factor.
Tissue factor (TF), also known as coagulation factor III (F3), is encoded by the gene mapped to human chromosome 1p21.3. TF has been shown to exist in two forms, namely membrane-bound and soluble TF. The encoded protein contains an extracellular domain (ED), a single transmembrane domain (TD) and short cytoplasmic domain (CD).
Tissue factor (TF), also known as coagulation factor III (F3), is encoded by the gene mapped to human chromosome 1p21.3. TF has been shown to exist in two forms, namely membrane-bound and soluble TF. The encoded protein contains an extracellular domain (ED), a single transmembrane domain (TD) and short cytoplasmic domain (CD).
Application
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human F3 / Tissue Factor ELISA Kit has been used to measure the concentration of soluble tissue factor (TF) expressed in human umbilical vein smooth muscle cells (HUVSMCs).
Human F3 / Tissue Factor ELISA Kit has been used to measure the concentration of soluble tissue factor (TF) expressed in human umbilical vein smooth muscle cells (HUVSMCs).
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Tissue factor (TF) interacts with the zymogen factor VII (VII) and its activated form VIIa, and initiates blood coagulation protease cascade. The encoded protein is involved in the pathogenesis of cardiovascular diseases, such as hypertension, atherosclerosis, acute coronary syndrome and restenosis. Thus, it is considered to be a potential therapeutic target for cardiovascular diseases.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Storage Class
10 - Combustible liquids
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