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Merck

SAB5702625

Anti-RAIDD/CRADD Antibody, clone 7M7M6, Rabbit Monoclonal

Synonym(s):

MRT34, RAIDD

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
7M7M6, monoclonal
Application:
IHC, WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

7M7M6, monoclonal

form

liquid

mol wt

23 kDa

species reactivity

rat, human

concentration

0.13 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

DTFLDSLQEFPWVREKLKKAREEAMTDLPAGDRLTGIPSHILNSSPSDRQINQLAQRLGPEWEPMVLSLGLSQTDIYRCKA

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CRADD(8738)

General description

This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 70-150 of human RAIDD/CRADD (P78560).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC


Storage Class

10 - Combustible liquids

wgk

WGK 1



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