SRP8033
IL-1β mouse
recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)
Synonym(s):
Interleukin-1beta, Postn
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About This Item
NACRES:
NA.32
UNSPSC Code:
12352202
Form:
lyophilized
Assay:
>95% (SDS-PAGE)
Biological source:
mouse
Recombinant:
expressed in E. coli
Mol wt:
~17 kDa by SDS-PAGE
biological source
mouse
recombinant
expressed in E. coli
conjugate
untagged
assay
>95% (SDS-PAGE)
form
lyophilized
mol wt
~17 kDa by SDS-PAGE
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
immunohistochemistry: suitable
impurities
<0.1 EU/μg endotoxin, tested
color
white
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Il1b(16176)
General description
Interleukin-1β (IL-1β) is produced by activated macrophages. It belongs to the IL-1 family of proteins that are involved in the inflammatory response.
Biochem/physiol Actions
Interleukin-1β (IL-1β) stimulates thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation and fibroblast growth factor activity. IL-1β, in most situations requires the inflammasome complex to be cleaved and secreted. This protein may modulate the effects of eosinophils in the intestine.
Physical form
Lyophilized from PBS.
Preparation Note
Reconstitute with 100 μL deionized water.
Other Notes
Mouse IL-1beta (aa 118-269) is untagged.
Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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IL-1? in eosinophil-mediated small intestinal homeostasis and IgA production.
Jung Y
Mucosal Immunology, 8(4), 930-942 (2015)
Understanding the mechanism of IL-1? secretion.
Lopez-Castejon G and Brough D
Cytokine & Growth Factor Reviews, 22(4), 189-195 (2011)
Ruojia Ma et al.
Drug development research, 83(3), 735-744 (2021-12-21)
Type 2 diabetes mellitus (T2DM) is a metabolic risk factor associated with non-alcoholic liver disease (NAFLD). Schisandrin B (Sch B) is a promising agent for NAFLD. However, the actions of Sch B on diabetes-associated NAFLD and the underlying mechanisms are