487957 Sigma-AldrichNOC-18 - CAS 146724-94-9 - Calbiochem
A nitric oxide (NO) donor similar to NOC-5, NOC-7 and NOC-12 but with an enhanced half-life.
More>> A nitric oxide (NO) donor similar to NOC-5, NOC-7 and NOC-12 but with an enhanced half-life. Less<<NOC-18 - CAS 146724-94-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: DETA/NO, 2,2ʹ-(Hydroxynitrosohydrazino)bis-ethanamine, DETA NONOate
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Overview
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Key Spec Table
| CAS # | Empirical Formula |
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| 146724-94-9 | C₄H₁₃N₅O₂ |
| Description | |
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| Overview | A nitric oxide (NO) donor similar to NOC-5 (Cat. No. 487950), NOC-7 (Cat. No. 487952) and NOC-12 (Cat. No. 487955) but with an enhanced half-life. Useful for the controlled release of NO in solution. Induces dose-dependent apoptosis in macrophages. Inhibits lipoprotein oxidation induced by Cu2+ in vitro. Half-life (t½) in PBS, pH 7.4 is 3400 minutes at 22°C. Relatively stable in alkaline solution (pH ≥10.0). |
| Catalogue Number | 487957 |
| Brand Family | Calbiochem® |
| Synonyms | DETA/NO, 2,2ʹ-(Hydroxynitrosohydrazino)bis-ethanamine, DETA NONOate |
| Product Information | |
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| CAS number | 146724-94-9 |
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₄H₁₃N₅O₂ |
| Chemical formula | C₄H₁₃N₅O₂ |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
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| Biological Information | |
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| Primary Target | A nitric oxide (NO) donor |
| Purity | ≥90% by HPLC |
| Physicochemical Information | |
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| Cell permeable | N |
| Dimensions |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Product Usage Statements |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 487957 | 0 |
Documentation
NOC-18 - CAS 146724-94-9 - Calbiochem MSDS
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NOC-18 - CAS 146724-94-9 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 487957 |
References
| Reference overview |
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| Seccia, M., et al. 1996. Biochem. Biophys. Res. Commun. 220, 306. Shibuta, S., et al. 1995. Neurosci. Lett. 187, 103. Shimaoka, M., et al. 1995. Biochem. Biophys. Res. Commun. 209, 519. Diodati, J.G., et al. 1993. J. Cardiovasc. Pharmacol. 22, 287. Hrabie, J.A., et al. 1993. J. Org. Chem. 58,1472. |