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Merck

295590

Nitrous oxide

99%

Synonym(s):

Dinitrogen monoxide, Laughing gas

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About This Item

Empirical Formula (Hill Notation):
N2O
CAS Number:
Molecular Weight:
44.01
UNSPSC Code:
12142100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
233-032-0
Beilstein/REAXYS Number:
8137358
MDL number:
Assay:
99%
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InChI key

GQPLMRYTRLFLPF-UHFFFAOYSA-N

InChI

1S/N2O/c1-2-3

SMILES string

[O-][N+]#N

vapor density

1.53 (15 °C, vs air)

vapor pressure

51.7 mmHg ( 21 °C)

assay

99%

bp

−88 °C (lit.)

mp

−91 °C (lit.)

Quality Level

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Application

  • Nitrous oxide allows selective oxygen atom transfer reactions while minimizing the risk of over-oxidation. Therefore, it is used to oxidize disilenes, silanimines, silaethenes and silylenes.
  • Along with Ru-porphyrin catalyst, it can be used in the epoxidation of olefins and steroids.
  • It can be used as an oxidant in for the metal-catalyzed oxidative homo- and cross-coupling of Grignard reagents.
  • N2O can also be used as a nitrogen-dopant source to synthesize p-type zinc oxide nanowires (ZnO NWs) via vapor-liquid-solid growth.

Packaging

Supplied in a carbon steel lecture bottle with a CGA180M/CGA110F needle valve installed.

Compatible with the following:
  • Aldrich® lecture-bottle station systems
  • Aldrich® lecture-bottle gas regulators

Other Notes

Legal Information

Aldrich is a registered trademark of Sigma-Aldrich Co. LLC

signalword

Danger

Hazard Classifications

Ox. Gas 1 - Press. Gas Liquefied gas - STOT SE 3

target_organs

Central nervous system

Storage Class

2A - Gases

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Git Lidman et al.
Developmental medicine and child neurology, 57(8), 754-761 (2015-03-27)
To investigate the effects of repeated botulinum toxin A (BoNT-A) injections combined with occupational therapy, including a splint, compared with occupational therapy alone on hand function in children with unilateral spastic cerebral palsy (USCP), in all International Classification of Functioning
Synthetic chemistry with nitrous oxide.
Severin K.
Chemical Society Reviews, 44(17), 6375-6386 (2015)
Roberta Corona et al.
Fertility and sterility, 100(6), 1777-1783 (2013-10-12)
To evaluate the effect of addition of nitrous oxide (N2O) to the carbon dioxide (CO2) pneumoperitoneum (PP) and the effect of blood, plasma, or red blood cells (RBCs) on postoperative adhesions in a laparoscopic mouse model. Prospective randomized controlled trial.
R L M Schils et al.
Animal : an international journal of animal bioscience, 7 Suppl 1, 29-40 (2012-10-04)
Herbivores are a significant source of nitrous oxide (N(2)O) emissions. They account for a large share of manure-related N(2)O emissions, as well as soil-related N(2)O emissions through the use of grazing land, and land for feed and forage production. It
Yan Chen et al.
Anesthesiology, 118(6), 1322-1331 (2013-04-04)
Nitrous oxide inactivates methionine synthase and may lead to DNA damage and wound infection. By using single-cell gel electrophoresis (comet assay), the authors determined the effect of nitrous oxide on DNA damage in circulating leukocytes. In this double-blind, randomized controlled

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