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Merck

928186

Gold nanoparticles

100 nm diameter, Alkyne functionalized, 1ml, OD 50, in water

Synonym(s):

AuNP, GdNP, Gold NP

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About This Item

UNSPSC Code:
12141717
NACRES:
NA.22

Product Name

Gold nanoparticles, 100 nm diameter, Alkyne functionalized, 1ml, OD 50, in water

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

description

Alkyne surface density: 1/nm2

concentration

in water

OD

50

core diam.

100 nm , coefficient of variance <12%

diameter

100 nm

λmax

572 nm

PDI

<0.200

functional group

alkyne

storage temp.

2-8°C

Quality Level

100

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Application

Ideal for development of gold conjugates for use in applications such as blotting, lateral flow assays, microscopy, and transmission electron microscopy (TEM).

General description

Alkyne functionalized gold nanoparticles are suitable for covalent conjugation of any azide-tagged molecule through Cu(I)-catalyzed click chemistry. These gold nanoparticles allow for rapid generation of gold conjugates for subsequent use in downstream assays.

Alkyne functionalized gold nanoparticles are more than 95% spherical and have uniform size distribution (CV <12%)

Preparation Note

When stored for a long period of time gold nanoparticles may sediment at the bottom of the vial, which is especially prominent for larger particle sizes. Prior to use, re-suspend the sedimented particles by thorough mixing until a homogenous solution is obtained.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Gold nanoparticles: synthesis and applications in drug delivery
Khan, A. K., et al
Tropical Journal of Pharmaceutical Research, 13.7, 1169-1177 (2014)
Wilson Luo et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 23(5), 1052-1059 (2016-10-12)
In this study, we report the design, synthesis, and characterization of small 3 nm water soluble gold nanoparticles (AuNPs) that feature cyclopropenone-masked strained alkyne moieties capable of undergoing interfacial strain-promoted cycloaddition (i-SPAAC) with azides after exposure to UV-A light. A strained
Mingmin Li et al.
Nanotheranostics, 3(1), 113-119 (2019-03-23)
Surface-enhanced Raman spectroscopy (SERS) has proven a powerful tool for multiplex detection and imaging due to its narrow peak width and high sensitivity. However, conventional SERS reporters are limited to thiolated compounds, which have limitations such as chemical stability and

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