Skip to Content
Merck

Key Documents

05-364

Sigma-Aldrich

Anti-Cdk5 Antibody, clone DC17

clone DC17, Upstate®, from mouse

Sign Into View Organizational & Contract Pricing
All Photos(4)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

DC17, monoclonal

species reactivity

mouse, human, Drosophila, rat

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NP_004926

UniProt accession no.

Q00535

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

fruit fly ... Cdk5(36727)
human ... CDK5(1020)
mouse ... Cdk5(12568)
rat ... Cdk5(140908)

General description

33kDa

Immunogen

Recombinant human cdk5

Application

Anti-Cdk5 Antibody, clone DC17 is a high quality Mouse Monoclonal Antibody for the detection of Cdk5 & has been validated in IP, WB, ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Biochem/physiol Actions

cdk5

Physical form

0.1M Tris-glycine pH 7.4, 0.15M NaCl, containing 0.05% sodium azide
Format: Purified
Protein G Chromatography

Preparation Note

2 years at -20°C

Analysis Note

Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
routinely evaluated by immunoblot on RIPA lysate from non-stimulated human A431 cells, mouse Wehi cells or rat PC12 cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

K Sobue et al.
The Journal of biological chemistry, 275(22), 16673-16680 (2000-04-06)
Neuronal Cdc2-like protein kinase (NCLK), a approximately 58-kDa heterodimer, was isolated from neuronal microtubules (Ishiguro, K., Takamatsu, M., Tomizawa, K., Omori, A., Takahashi, M., Arioka, M., Uchida, T. and Imahori, K. (1992) J. Biol. Chem. 267, 10897-10901). The biochemical nature
S R Floyd et al.
The Journal of biological chemistry, 276(11), 8104-8110 (2000-12-13)
Amphiphysin 1 is a phosphoprotein expressed at high levels in neurons, where it participates in synaptic vesicle endocytosis and neurite outgrowth. It is a substrate for cyclin-dependent kinase (cdk) 5, a member of the cyclin-dependent protein kinase family, which has
Both the establishment and maintenance of neuronal polarity require the activity of protein kinase D in the Golgi apparatus.
Yin, DM; Huang, YH; Zhu, YB; Wang, Y
The Journal of Neuroscience null
The presence of active Cdk5 associated with p35 in astrocytes and its important role in process elongation of scratched astrocyte.
Yi He,Hui-Li Li,Wei-Yan Xie,Chun-Zhang Yang,Albert Cheung Hoi Yu,Yun Wang
Glia null
Weiyan Xie et al.
International journal of biological sciences, 10(2), 192-199 (2014-02-20)
Pituitary tumors are monoclonal adenomas that account for about 10-15% of intracranial tumors. Cyclin-dependent kinase 5 (CDK5) regulates the activities of various proteins and cellular processes in the nervous system, but its potential roles in pituitary adenomas are poorly understood.
View All Related Papers

Global Trade Item Number

SKUGTIN
05-36404053252273803

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service