05-883
Anti-tPA (Tissue Plasminogen Activator) Antibody, clone GMA-043
clone GMA-043, Upstate®, from mouse
Synonym(s):
Anti-BAT-PA, Anti-DSPA-5
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
GMA-043, monoclonal
Application:
ELISA, WB
Citations:
8
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
GMA-043, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
ELISA: suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... PLAT(5327)
mouse ... Plat(18791)
General description
Mr 63kDa
Immunogen
Purified human tissue plasminogen activator (tPA)
Application
Detect tPA (Tissue Plasminogen Activator) using this Anti-tPA (Tissue Plasminogen Activator) Antibody, clone GMA-043 validated for use in ELISA & WB.
Research Category
Metabolism
Metabolism
Research Sub Category
Enzymes & Biochemistry
Enzymes & Biochemistry
Biochem/physiol Actions
tPA
Physical form
100 µg of protein G purified mouse IgG1 lyophilized from 10 mM NaH2PO4, 0.15 M NaCl, 1.0% mannitol, pH 7.4.
Format: Purified
Protein G Purified
Preparation Note
stable 2 years at -20°C from date of shipment
Analysis Note
routinely evaluated by immunoblot on human tPA
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
Certificates of Analysis (COA)
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Stella E Tsirka
Biochemical Society transactions, 30(2), 222-225 (2002-05-25)
The tissue plasminogen activator (tPA)/plasmin proteolytic system has been implicated in both physiological and pathological processes in the mammalian brain. The physiological roles include facilitating neurite outgrowth and pathfinding. The pathological role involves mediating a critical step in the progression
Tissue-type plasminogen activator: characteristics, applications and production technology.
Rouf, S A, et al.
Biotechnology Advances, 14, 239-266 (1996)
Liudi Yao et al.
The Journal of biological chemistry, 297(3), 101096-101096 (2021-08-22)
Idiopathic pulmonary fibrosis (IPF) is the prototypic progressive fibrotic lung disease with a median survival of 2 to 4 years. Injury to and/or dysfunction of the alveolar epithelium is strongly implicated in IPF disease initiation, but the factors that determine whether
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 05-883 | 04053252670435 |