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Merck

05-954

Anti-TCL1 Antibody

culture supernatant, Upstate®

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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Product Name

Anti-TCL1 Antibody, culture supernatant, Upstate®

biological source

mouse

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_021966

UniProt accession no.

P56279

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... TCL1A(8115)

Analysis Note

Routinely evaluated by immunoblot in RIPA lysates from Raji cells

Application

Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
This Anti-TCL1 Antibody is validated for use in WB, IH for the detection of TCL1.

Biochem/physiol Actions

TCL1A, no cross-reactivity with TML1 (TCL1B) or MTCP1

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

14 kD

Immunogen

KLH-conjugated, synthetic peptide corresponding to amino acids 60-73 (RPMTPTQIGPSLLP) of human TCL1A

Physical form

Cell culture supernatant

Preparation Note

2 years at -20°C from date of shipment

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 1

Certificates of Analysis (COA)

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TCL1 is a diagnostic marker for intratubular germ cell neoplasia and classic seminoma.
Dengfeng Cao,Zhaoli Lane,Robert William Allan,Peng Wang,Charles Chuanhai Guo,Yan Peng,Jianping Li
Histopathology null
A systematic approach to diagnosis of mature T-cell leukemias reveals heterogeneity among WHO categories
Herling, M. et al.
Blood, 104, 328-335 (2004)
Structural basis for the co-activation of protein kinase B by T-cell leukemia-1 (TCL1) family proto-oncoproteins.
Auguin, Daniel, et al.
The Journal of Biological Chemistry, 279, 35890-35902 (2004)
TCL1: a new drug target in lymphoid and germ-cell malignancies?
Lock, Richard B
The International Journal of Biochemistry & Cell Biology, 35, 1614-1618 (2003)
Crystal structures of Tcl1 family oncoproteins and their conserved surface features.
Petock, John M, et al.
TheScientificWorldJournal, 2, 1876-1884 (2002)
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Global Trade Item Number

SKUGTIN
05-95404053252671753

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