Skip to Content
Merck

06-1367

Anti-SRp75 Antibody

from rabbit

Synonym(s):

serine/arginine-rich splicing factor 4, splicing factor, arginine/serine-rich 4, SR splicing factor 4, Pre-mRNA-splicing factor SRP75

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Anti-SRp75 Antibody, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse, rat

technique(s)

western blot: suitable

NCBI accession no.

NP_005617

UniProt accession no.

Q08170

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... SRSF4(6429)

Analysis Note

Evaluated by Western Blot in L6 cell lysate.

Western Blot Analysis: 1:500 dilution of this antibody detected SRp75 on 10 µg of L6 cell lysate.

Application

Anti-SRp75 Antibody is a rabbit polyclonal antibody for detection of SRp75 also known as serine/arginine-rich splicing factor 4, SR splicing factor 4, Pre-mRNA-splicing factor SRP75 & has been validated in WB.
Immunoprecipitation Analysis: A reprentative lot of this antibody was used by an independent laboratory in IP. (Jiang, K., et al. (2009). Endocrinology. 150(5):2087-2097.)

General description

SRp75, also known as Serine/arginine-rich splicing factor 4, is an essential splicing factor that is a member of the SR family of proteins. This protein is a component of the pre-mRNA splicing complex and is believed to play a role in alternative splice site selection. Consistent with this excess levels of SRp75 have been shown to play a role in alternative splicing of CD45. SRp75 is normally found in the nucleus and is known to be hyperphosphorylated at serine residues in its RS domain.
~ 62 kDa observed

Immunogen

KLH-conjugated linear peptide corresponding to human SRp75.

Physical form

Format: Purified

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Paul L Boutz et al.
Genes & development, 29(1), 63-80 (2015-01-07)
Deep sequencing of embryonic stem cell RNA revealed many specific internal introns that are significantly more abundant than the other introns within polyadenylated transcripts; we classified these as "detained" introns (DIs). We identified thousands of DIs, many of which are
Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins.
Hinkle, et al.
Communications biology, 5, 987-987 (2022)

Global Trade Item Number

SKUGTIN
06-136704053252749506

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service