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Merck

06-588

Anti-STAT5A/B Antibody

serum, Upstate®

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-STAT5A/B Antibody, serum, Upstate®

biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat, human, sheep

manufacturer/tradename

Upstate®

technique(s)

electrophoretic mobility shift assay: suitable

isotype

IgG

NCBI accession no.

NM_003152.2

UniProt accession no.

P42229

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... STAT5A(6776)

Analysis Note

routinely evaluated by Supershift

Application

Detect STAT5A/B also known as signal transducer & activator of transcription 5A/B with Anti-STAT5A/B Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in EMSA.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

Biochem/physiol Actions

STAT5A and B

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

90-95 kDa

Immunogen

peptide (CQELQKKAEHQVGEDG), corresponding to amino acids 66-80 of human STAT5 A and B

Other Notes

Replaces: 04-1016

Physical form

Antiserum
whole rabbit antiserum containing 0.05% sodium azide

Preparation Note

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 1

Certificates of Analysis (COA)

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Distinct pathways involving the FK506-binding proteins 12 and 12.6 underlie IL-2-versus IL-15-mediated proliferation of T cells.
Dubois, S; Shou, W; Haneline, LS; Fleischer, S; Waldmann, TA; Muller, JR
Proceedings of the National Academy of Sciences of the USA null
A novel model of SCID-X1 reconstitution reveals predisposition to retrovirus-induced lymphoma but no evidence of gammaC gene oncogenicity.
Linda Scobie,Ralph D Hector,Louise Grant,Margaret Bell,Anne A Nielsen,Sharon Meikle et al.
Molecular Therapy null
Convergence of progesterone and epidermal growth factor signaling in breast cancer. Potentiation of mitogen-activated protein kinase pathways
Lange, C. A., et al
The Journal of Biological Chemistry, 273, 31308-31316 (1998)
Novel role for STAT-5B in the regulation of Hsp27-FGF-2 axis facilitating thrombin-induced vascular smooth muscle cell growth and motility.
Cao, H; Dronadula, N; Rizvi, F; Li, Q; Srivastava, K; Gerthoffer, WT; Rao, GN
Circulation Research null
J X Lin et al.
Immunity, 2(4), 331-339 (1995-04-01)
To understand the molecular bases for cytokine redundancy and pleiotropy, we have compared the Stat proteins activated in peripheral blood lymphocytes (PBLs) by cytokines with shared and distinct actions. Interleukin-2 (IL-2) rapidly activated Stat5 in fresh PBL, and Stat3 and
View All Related Papers

Related Content

JAK/STAT Signaling Research Focus

The Janus kinase (JAK)/signal transducers and activators of transcription (STAT) signaling pathway plays an important role in cell proliferation, cell differentiation, cell migration, and cell death. It is the principal signaling mechanism for a variety of cytokines and growth factors. Constitutive activation or dysregulation of JAK/STAT signaling can result in inflammatory disease, erythrocytosis, gigantism, and leukemia.

Global Trade Item Number

SKUGTIN
06-58804053252282331

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