06-709

Anti-Gq/11α Antibody, CT

Name: Anti-Gq/11α Antibody, CT
Brand: MM

Upstate^®, from rabbit

Synonym(s):

Anti-FBH, Anti-FHH2, Anti-GNA-11, Anti-HG1K, Anti-HHC2, Anti-HYPOC2

Sign Into View Organizational & Contract Pricing

Select a Size

All Photos(2)

About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate^®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_002067
NM_002072

UniProt accession no.

P29992

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... GNA11(2767)
mouse ... Gna11(14672)

General description

42kDa

Immunogen

peptide (QLNLKEYNLV) corresponding to amino acids 350-359 of Gqα or G11α

Application

Research Category
Signaling

Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling

This Anti-Gq/11α Antibody, CT is validated for use in IP, WB for the detection of Gq/11α.

Biochem/physiol Actions

Gqα and G11α

Physical form

Format: Purified

PBS, pH 7.4

Protein A chromatography

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot on rat brain microsomal preparation

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Dystrophic mdx mouse myoblasts exhibit elevated ATP/UTP-evoked metabotropic purinergic responses and alterations in calcium signalling.

Justyna Róg et al.

Biochimica et biophysica acta. Molecular basis of disease, 1865(6), 1138-1151 (2019-01-27)

Pathophysiology of Duchenne Muscular Dystrophy (DMD) is still elusive. Although progressive wasting of muscle fibres is a cause of muscle deterioration, there is a growing body of evidence that the triggering effects of DMD mutation are present at the earlier

Involvement of G alpha q/11 in the contractile signal transduction pathway of muscarinic M3 receptors in caecal smooth muscle.

P Cuq et al.

European journal of pharmacology, 315(2), 213-219 (1996-11-14)

The nature of the pertussis toxin-insensitive G-protein involved in muscarinic-mediated phosphoinositides breakdown and contraction of isolated smooth muscle cells from the circular layer of the rabbit caecum was investigated. Immunoblotting of membrane proteins using affinity purified antibodies directed against different

4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha(q/11).

Blanc, E M, et al.

Journal of Neurochemistry, 69, 570-580 (1997)

Molecular characterization of host-parasite cell signalling in Schistosoma mansoni during early development.

Margarida Ressurreição et al.

Scientific reports, 6, 35614-35614 (2016-10-21)

During infection of their human definitive host, schistosomes transform rapidly from free-swimming infective cercariae in freshwater to endoparasitic schistosomules. The 'somules' next migrate within the skin to access the vasculature and are surrounded by host molecules that might activate intracellular

A regulatory loop between miR-132 and miR-125b involved in gonadotrope cells desensitization to GnRH.

Jérôme Lannes et al.

Scientific reports, 6, 31563-31563 (2016-08-20)

The GnRH neurohormone is the main activator of the pituitary gonadotropins, LH and FSH. Here we investigated the contribution of microRNAs in mediating GnRH activation. We first established that miR-125b targets several actors of Gαq/11 signalling pathway, without altering Gαs

View All Related Papers

Global Trade Item Number

SKU	GTIN
06-709	04053252276491

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service