07-1407

Anti-GLUT-8 Antibody, CT

Name: Anti-GLUT-8 Antibody, CT
Brand: MM

from rabbit

Synonym(s):

Glucose transporter type 8, Glucose transporter type X1, glucose transporter X1, solute carrier family 2 (facilitated glucose transporter)

member 8, solute carrier family 2 (facilitated glucose transporter),

member 8

Select a Size

All Photos(1)

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Product Name

Anti-GLUT-8 Antibody, CT, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

species reactivity (predicted by homology)

mouse

technique(s)

immunohistochemistry: suitable (paraffin)

UniProt accession no.

Q9NY64

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... SLC2A8(29988)
mouse ... Slc2A8(56017)

Physical form

Liquid in PBS with 0.1% BSA.

Format: Purified

ImmunoAffinity Purified

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Replaces: AB3140

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Analysis Note

Control
Human kidney tissue.

Evaluated by Immunohistochemistry in human kidney tissue
Immunohistochemistry Analysis: 1:100 dilution of this lot detected GLUT-8 in human kidney tissue.

Application

Anti-GLUT-8 Antibody, C-terminus detects level of GLUT-8 & has been published & validated for use in IH(P).

Research Category
Signaling

Research Sub Category
Insulin/Energy Signaling

Biochem/physiol Actions

Recognizes GLUT-8.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Approx. 50 kDa

GLUT-8 is a glucose transporter facilitated by the regulation of insulin, binding cytochalasin B such that the orientation is glucose-inhibitive. In appearance, the transporter seems to be a dual-specific sugar transporter since fructose can also be inhibitive. GLUT-8 is expressed largely in the testis, where down-regulation is facilitated by estrogen. However, GLUT-8 is not highly expressed in testicular carcinoma. Lower levels of GLUT-8 are present in most other tissues.

Immunogen

An 11 amino acid sequence near the C-terminus of mouse Glut-8 (Doege et al. 2000; Carayannopoulos et al. 2000)

Epitope: C-terminus

Not finding the right product?

Try our Product Selector Tool.

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Tau reduction in aged mice does not impact Microangiopathy.

Rachel E Bennett et al.

Acta neuropathologica communications, 8(1), 137-137 (2020-08-20)

Microangiopathy, including proliferation of small diameter capillaries, increasing vessel tortuosity, and increased capillary blockage by leukocytes, was previously observed in the aged rTg4510 mouse model. Similar gene expression changes related to angiogenesis were observed in both rTg4510 and Alzheimer's disease

Serotonin (5-HT) affects expression of liver metabolic enzymes and mammary gland glucose transporters during the transition from pregnancy to lactation.

Jimena Laporta et al.

PloS one, 8(2), e57847-e57847 (2013-03-08)

The aim of this experiment was to demonstrate the ability of feeding serotonin (5-HT; 5-hydroxytryptamine) precursors to increase 5-HT production during the transition from pregnancy to lactation and the effects this has on maternal energy metabolism in the liver and

Global Trade Item Number

SKU	GTIN
07-1407	04053252475573

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service