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Merck

07-394

Anti-MAGE-D1/NRAGE Antibody

serum, Upstate®

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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Product Name

Anti-MAGE-D1/NRAGE Antibody, serum, Upstate®

biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, mouse, human

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_006986

UniProt accession no.

Q9Y5V3

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... MAGED1(9500)

Analysis Note

routinely evaluated by immunoblot in RIPA lysates from PC12 cells

Application

Anti-MAGE-D1/NRAGE Antibody is an antibody against MAGE-D1/NRAGE for use in IP, WB, IH.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Developmental Neuroscience

Biochem/physiol Actions

NRAGE/MAGE-D1

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

90-96 kDa

Immunogen

GST fusion protein corresponding to residues 53-295 of rat MAGE-D1/NRAGE

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, before the addition of glycerol to 30%
Antiserum

Preparation Note

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 2

Certificates of Analysis (COA)

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Amir H Salehi et al.
The Journal of biological chemistry, 277(50), 48043-48050 (2002-10-12)
The p75 neurotrophin receptor (p75NTR) mediates signaling events leading to activation of the JNK pathway and cell death in a variety of cell types. We recently identified NRAGE, a protein that directly interacts with the p75NTR cytosolic region and facilitates
A H Salehi et al.
Neuron, 27(2), 279-288 (2000-09-14)
The mechanisms employed by the p75 neurotrophin receptor (p75NTR) to mediate neurotrophin-dependent apoptosis are poorly defined. Two-hybrid analyses were used to identify proteins involved in p75NTR apoptotic signaling, and a p75NTR binding partner termed NRAGE (for neurotrophin receptor-interacting MAGE homolog)
Jennifer M Doyle et al.
Molecular cell, 39(6), 963-974 (2010-09-25)
The melanoma antigen (MAGE) family consists of more than 60 genes, many of which are cancer-testis antigens that are highly expressed in cancer and play a critical role in tumorigenesis. However, the biochemical and cellular functions of this enigmatic family

Global Trade Item Number

SKUGTIN
07-39404053252365409

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