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Merck

07-531

Anti-PIR121-1/Sra-1 Antibody

Upstate®, from rabbit

Synonym(s):

Cytoplasmic FMR1-interacting protein 1, Specifically Rac1-associated protein 1, Sra-1, p140sra-1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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Product Name

Anti-PIR121-1/Sra-1 Antibody, Upstate®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... CYFIP1(23191)
mouse ... Cyfip1(20430)

Analysis Note

routinely evaluated by immunoblot on RIPA homogenates from rat brain

Application

Anti-PIR121-1/Sra-1 Antibody is an antibody against PIR121-1/Sra-1 for use in IP & WB.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

Biochem/physiol Actions

PIR121-1/Sra-1 (aka CYFIP1)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Mr~130kDa

Immunogen

KLH-conjugated, synthetic peptide corresponding to amino acids 872-886 (SQEFQRDKQPNAQPQ-C) of human PIR121-1/Sra-1, with a C-terminal cysteine added for conjugation purposes.

Physical form

Format: Purified
Protein A purified

Preparation Note

stable 2 years at -20°C from date of shipment

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 1


Certificates of Analysis (COA)

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S L Blagg et al.
Biochemical Society transactions, 32(Pt 6), 1113-1114 (2004-10-28)
The WASP (Wiskott-Aldrich syndrome protein)/SCAR (suppressor of cAMP receptor) family of adaptor proteins regulate actin polymerization by coupling Rho-family GTPases to the activation of the Arp2/3 complex. SCAR exists within a complex of proteins, including Nap1 (Nck-associated protein 1), PIR121
E Saller et al.
The EMBO journal, 18(16), 4424-4437 (1999-08-17)
p53 mutants in tumours have a reduced affinity for DNA and a reduced ability to induce apoptosis. We describe a mutant with the opposite phenotype, an increased affinity for some p53-binding sites and an increased ability to induce apoptosis. The
The ARP2/3 complex: giving plant cells a leading edge.
Mathur, Jaideep
Bioessays, 27, 377-387 (2005)
Marco A Salazar et al.
The Journal of biological chemistry, 278(49), 49031-49043 (2003-09-25)
Tuba is a novel scaffold protein that functions to bring together dynamin with actin regulatory proteins. It is concentrated at synapses in brain and binds dynamin selectively through four N-terminal Src homology-3 (SH3) domains. Tuba binds a variety of actin
Local F-actin network links synapse formation and axon branching.
Chia, PH; Chen, B; Li, P; Rosen, MK; Shen, K
Cell null

Global Trade Item Number

SKUGTIN
07-53104053252402937

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