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Merck

07-548

Anti-monomethyl-Histone H3 (Lys36) Antibody

serum, Upstate®

Synonym(s):

H3K36me1, Histone H3 (mono methyl K36)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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Product Name

Anti-monomethyl-Histone H3 (Lys36) Antibody, serum, Upstate®

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

vertebrates

manufacturer/tradename

Upstate®

technique(s)

dot blot: suitable
immunofluorescence: suitable
multiplexing: suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

monomethylation (Lys36)

Quality Level

Gene Information

human ... H3F3B(3021)

Analysis Note

routinely evaluated by immunoblot in chicken core histones

Application

Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones
Use Anti-monomethyl-Histone H3 (Lys36) Antibody (Rabbit Polyclonal Antibody) validated in DB, IF, WB, Mplex to detect monomethyl-Histone H3 (Lys36) also known as H3K36me1, Histone H3 (monomethyl K36).

Biochem/physiol Actions

monomethyl-Histone H3 (Lys36)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

17kDa

Immunogen

Peptide containing the sequence GVmeKKP corresponding to monomethyl Lysine 36 of human histone H3 .

Physical form

0.05% sodium azide and 30% glycerol
Antiserum

Preparation Note

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate.
Li, Yan, et al.
The Journal of Biological Chemistry, 284, 34283-34295 (2009)
Changhui Sun et al.
The Plant cell, 24(8), 3235-3247 (2012-08-16)
Chromatin modifications affect flowering time in the long-day plant Arabidopsis thaliana, but the role of histone methylation in flowering time regulation of rice (Oryza sativa), a short-day plant, remains to be elucidated. We identified a late-flowering long vegetative phase1 (lvp1)
Autocatalytic differentiation of epigenetic modifications within the Arabidopsis genome.
Inagaki, S; Miura-Kamio, A; Nakamura, Y; Lu, F; Cui, X; Cao, X; Kimura, H; Saze, H; Kakutani, T
The Embo Journal null
Shuzhi Zheng et al.
Nature communications, 10(1), 1303-1303 (2019-03-23)
In plants, flowering time is controlled by environmental signals such as day-length and temperature, which regulate the floral pathway integrators, including FLOWERING LOCUS T (FT), by genetic and epigenetic mechanisms. Here, we identify an H3K27me3 demethylase, JUMONJI 13 (JMJ13), which
Han-Sae Lee et al.
The EMBO journal, 29(8), 1434-1445 (2010-03-13)
Although recent studies highlight the importance of histone modifications and ATP-dependent chromatin remodelling in DNA double-strand break (DSB) repair, how these mechanisms cooperate has remained largely unexplored. Here, we show that the SWI/SNF chromatin remodelling complex, earlier known to facilitate

Related Content

"Epigenetics describes heritable changes in gene expression caused by non-genetic mechanisms instead of by alterations in DNA sequence. These changes can be cell- or tissue-specific, and can be passed on to multiple generations. Epigenetic regulation enriches DNAbased information, allowing a cell to vary its response across diverse biological and environmental contexts. Although epigenetic mechanisms are primarily centered in the nucleus, these mechanisms can be induced by environmental signals such as hormones, nutrients, stress, and cellular damage, pointing to the involvement of cytoplasmic and extracellular factors in epigenetic regulation."

Global Trade Item Number

SKUGTIN
07-54804053252409493

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