Skip to Content
Merck

07-631

Anti-cdk2 Antibody

Upstate®, from rabbit

Synonym(s):

Anti-CDKN2, Anti-p33(CDK2)

Sign In to View Organizational & Contract Pricing.

Select a Size

All Photos(1)

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-cdk2 Antibody, Upstate®, from rabbit

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_001798

UniProt accession no.

P24941

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... CDK2AP1(8099)

biological source

rabbit

conjugate

unconjugated

antibody form

purified antibody

Analysis Note

Control
Colon tissue
routinely evaluated by immunoblot in nuclear extracts from HeLa cells

Application

Anti-cdk2 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of cdk2 & has been validated in IP & WB.

Biochem/physiol Actions

Predicted to cross-react with mouse, rat, non-human primates, and hamster based on sequence homology
Recognizes human p33cdk2 protein kinase.

General description

33 kDa

Immunogen

peptide corresponding to amino acids 287-298 (C-QDVTKPVPHLRL) of human cdk2

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

10 - Combustible liquids

wgk

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Carlotta Costa et al.
Cancer discovery, 10(1), 72-85 (2019-10-09)
The combination of CDK4/6 inhibitors with antiestrogen therapies significantly improves clinical outcomes in ER-positive advanced breast cancer. To identify mechanisms of acquired resistance, we analyzed serial biopsies and rapid autopsies from patients treated with the combination of the CDK4/6 inhibitor
Sublytic complement attack induces cell cycle in oligodendrocytes.
Rus, H G, et al.
Journal of immunology (Baltimore, Md. : 1950), 156, 4892-4900 (1996)
Sonya Hui et al.
Circulation research, 108(9), 1053-1062 (2011-03-05)
Cell cycle progression in vascular smooth muscle cells (VSMCs) is a therapeutic target for restenosis. Having discovered that calmodulin (CaM)-dependent cyclin E/CDK2 activity underlies Ca(2+)-sensitive G(1)-to-S phase transitions in VSMCs, we sought to explore the physiological importance of the CaM-cyclin
C S Rani et al.
The Journal of biological chemistry, 272(16), 10777-10783 (1997-04-18)
Platelet-derived growth factor (PDGF) and serum, but not epidermal growth factor (EGF), stimulated sphingosine kinase activity in Swiss 3T3 fibroblasts and increased intracellular concentrations of sphingosine 1-phosphate (SPP), a sphingolipid second messenger (Olivera, A., and Spiegel, S. (1993) Nature 365
CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle.
Elledge, S J, et al.
Proceedings of the National Academy of Sciences of the USA, 89, 2907-2911 (1992)
View All Related Papers

Global Trade Item Number

SKUGTIN
07-63104053252369995

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service