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Merck

07-879

Anti-phospho-PKCγ (Thr655) Antibody

Upstate®, from rabbit

Synonym(s):

PRKCG, PKC-gamma, PKCC, PKCG, SCA14, Protein Kinase C gamma

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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biological source

rabbit

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_002739.3

UniProt accession no.

P05129

shipped in

dry ice

target post-translational modification

phosphorylation (pThr655)

Gene Information

human ... PRKCG(5582)

General description

78.5 kDa

Immunogen

Peptide corresponding to amino acid region encompassing the human, mouse, and rat phospho-PKCγ (Thr655).

Application

Anti-phospho-PKCγ (Thr655) Antibody detects level of phospho-PKCγ (Thr655) & has been published & validated for use in WB.

Biochem/physiol Actions

Predicted to cross-react with mouse and rat based on complete sequence homology, but have not been tested.
Recognizes phosphor-PKCγ (Thr655). PKCα and PKCβII may cross react in high expressing cells.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Takahiro Seki et al.
The Journal of biological chemistry, 280(32), 29096-29106 (2005-06-21)
Spinocerebellar ataxia type 14 (SCA14) is an autosomal dominant neurodegenerative disease characterized by various symptoms including cerebellar ataxia. Recently, several missense mutations in the protein kinase Cgamma (gammaPKC) gene have been found in different SCA14 families. To elucidate how the
Yu-Wen Tseng et al.
Frontiers in cellular and infection microbiology, 11, 613195-613195 (2021-03-30)
Streptococcus pneumoniae is one of most deadly Gram-positive bacterium that causes significant mortality and morbidity worldwide. Intense inflammation and cytotoxicity is a hallmark of invasive pneumococcal disease. Pneumococcal NanA has been shown to exaggerate the production of inflammatory cytokines via

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