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Merck

09-230

Anti-phospho-Raptor (Thr706) Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

P150 target of rapamycin (TOR)-scaffold protein, p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats, regulatory associated protein of mTOR

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
canine, human
Application:
DB, WB
Citations:
1
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biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

canine, human

species reactivity (predicted by homology)

horse (based on 100% sequence homology), mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), dog (based on 100% sequence homology), rat (based on 100% sequence homology)

technique(s)

dot blot: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

phosphorylation (pThr706)

Gene Information

bovine ... Rptor(507056)
human ... RPTOR(57521)

General description

Raptor is a subunit of mTORC1 which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Within mTORC1, Raptor positively regulates mTORC1 activity and functions as a scaffold for recruiting mTORC1 substrates.
~ 150 kDa

Immunogen

Epitope: Ser706
KLH-conjugated linear peptide corresponding to human Raptor phosphorylated at and around Thr706.

Application

Detect phospho-Raptor (Thr706) using this Anti-phospho-Raptor (Thr706) Antibody validated for use in WB, DB.

Biochem/physiol Actions

This antibody recognizes Raptor phosphorylated at Thr706.

Physical form

Purified rabbit serum in PBS with 0.05% sodium azide.

Analysis Note

Control
Modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein
Evaluated by Dot Blot in modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein.

Dot Blot Analysis: 1 µg/mL of this antibody detected Raptor in modified and non-modified peptides of phosphorylated and non-phosphorlyated Raptor protein.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

12 - Non Combustible Liquids



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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