09-796

Anti-PADI4 Antibody, CT

Name: Anti-PADI4 Antibody, CT
Brand: MM

from rabbit

Synonym(s):

HL-60 PAD, PADI-H protein, Peptidylarginine deiminase IV, Protein-arginine deiminase type IV, peptidyl arginine deiminase, type IV, peptidyl arginine deiminase, type V, protein-arginine deiminase, Protein-arginine deiminase type-4

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Product Name

Anti-PADI4 Antibody, CT, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

technique(s)

ELISA: suitable
western blot: suitable

NCBI accession no.

NP_036519

UniProt accession no.

Q9UM07

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... PADI4(23569)

Analysis Note

Control
HEK293 cell lysate

Evaluated by western blot on HEK293 cell lysate.

Western Blotting Analysis: 1:25-1:500 dilution of this antibody detected PADI4 in HEK293 cell lysate.

Application

Anti-PADI4 Antibody, C-terminus is an antibody against PADI4 for use in WB, ELISA.

ELISA: A 1:1000 dilution of a previous lot was used on ELISA.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

Biochem/physiol Actions

The antibody recognizes PADI4 at and around the C-terminus.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

PADI4 (Protein-arginine deiminase type-4) is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalysis of the deimination of the arginine residues. PADI4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.

~74 kDa

Immunogen

Epitope: C-terminus

KLH-conjugated synthetic linear peptide corresponding to the C-terminal region of PADI4.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Purified rabbit polyclonal in buffer containing PBS and 0.09% sodium azide.

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Preparation Note

Stable for 6 months at 2-8ºC from date of receipt. For long term storage, store at -20ºC

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c