Anti-eIF4A3 Antibody

Eukaryotic translation initiation factor 4A, isoform 3, also known as eIF4A3, is a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. eIF4A3 is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

~34 kDa

This antibody detects RNA-binding protein eIF4A3.

KLH-conjugated synthetic linear peptide corresponding to eIF4A3.

Anti-eIF4A3 Antibody is a rabbit polyclonal antibody for detection of eIF4A3 also known as ATP-dependent RNA helicase DDX48, Eukaryotic translation initiation factor 4A isoform 3 & has been validated in WB.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
RNA Binding Protein (RBP)

Rabbit polyclonal serum with 0.05% sodium azide.

Unpurified

Stable for 1 year at -20ºC from date of receipt.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Control
A431 cell lysate

Evaluated by western blot on A431 cell lysate.
Western Blot Analysis: 1:1000 dilution of this antibody detected eIF4A3 in A431 cell lysate.

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